New combo therapy shows promise for lung cancer patients with brain tumors

NCT ID NCT07491211

First seen Mar 26, 2026 · Last updated Apr 25, 2026 · Updated 3 times

Summary

This study looks at 300 adults with a specific type of lung cancer (EGFR-mutant) that has spread to the brain and is causing symptoms. Researchers want to see if giving a targeted pill (osimertinib) together with precise brain radiation helps control the cancer longer than the drug alone. The goal is to improve how long patients live without the cancer growing, while monitoring side effects like brain swelling.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, China, 200032, China

  • Shanghai Jiao Tong University Affiliated Chest Hospital

    Shanghai, China

  • Wuhan Tongji Hospital

    Wuhan, Hubei, China

Conditions

Explore the condition pages connected to this study.