Edwards Lifesciences

This study tests a new device called the Edwards EVOQUE system to replace the tricuspid valve in people with severe tricuspid regurgitation (leaky valve). The goal is to see if the device is safe and can reduce the leak, improve symptoms, and enhance quality of life. About 864 ad…

This study looks at the SAPIEN 3 Ultra heart valve in 200 people with severe, symptomatic aortic stenosis who are at intermediate or higher risk for open-heart surgery. The goal is to see if the valve works well and is safe, measuring things like survival, need for repeat procedu…

This study looks at a new way to treat heart valves used in surgery to replace damaged aortic or mitral valves. About 777 adults who need a valve replacement will get these specially treated valves and be followed for up to 5 years. The goal is to make sure the new treatment is s…

This study tests a new device called the Edwards EVOQUE eos mitral valve replacement system in 123 people with a leaky mitral valve who are too high-risk for open-heart surgery. The goal is to see if the device is safe and works well to control the disease. Participants receive t…

This study is checking how well a new valve system works in people born with heart defects that cause a leaky pulmonary valve. About 150 participants who need a new valve will get the Edwards SAPIEN 3 system. Researchers will track if the valve is placed correctly and works well …

This study tests a device called the Edwards APTURE shunt, which is placed in the heart to help reduce pressure and improve symptoms in people with heart failure. About 100 participants will be randomly assigned to receive the shunt or a sham procedure. The goal is to see if the …

This study is testing a new heart valve (SAPIEN 3) for people born with heart defects that have a damaged or failing valve in the pulmonary position. About 150 participants will receive the valve through a tube inserted in a blood vessel, avoiding open-heart surgery. The goal is …

This early study tests a device that creates a small passage in the heart to help reduce pressure and improve symptoms in people with heart failure. About 71 participants who have ongoing symptoms despite standard medications will be enrolled. The goal is to see if the device is …