New heart valve offers hope without Open-Heart surgery

NCT ID NCT04860765

First seen Feb 03, 2026 · Last updated Apr 29, 2026 · Updated 9 times

Summary

This study is testing a new heart valve (SAPIEN 3) for people born with heart defects that have a damaged or failing valve in the pulmonary position. About 150 participants will receive the valve through a tube inserted in a blood vessel, avoiding open-heart surgery. The goal is to see if the valve works well and improves blood flow from the heart to the lungs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advocate Childrens Hospital

    Oak Lawn, Illinois, 60453, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars Sinai

    Los Angeles, California, 90048, United States

  • Children's Health Dallas

    Dallas, Texas, 75235, United States

  • Children's Hospital of Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinatti Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Columbia University Medical Center/NYPH

    New York, New York, 10032, United States

  • Dell Children's

    Austin, Texas, 78723, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Minneapolis Heart

    Minneapolis, Minnesota, 55407, United States

  • Mount Sinai

    New York, New York, 10029, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43215, United States

  • Newark Beth Israel Medical Center

    Newark, New Jersey, 07112, United States

  • Primary Children's

    Salt Lake City, Utah, 84108, United States

  • St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

  • University of Alabama

    Birmingham, Alabama, 35487, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 19146, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.