New heart valve system offers hope for patients with leaky pulmonary valves

NCT ID NCT05378386

First seen Nov 05, 2025 · Last updated Jun 14, 2026 · Updated 30 times

Summary

This study looks at a new device to fix leaky pulmonary valves in people born with heart defects. About 150 people will get the Edwards SAPIEN 3 valve placed inside a special stent. The goal is to see if the valve works well and stays in place without major problems.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advocate Children's Hospital

    Oak Lawn, Illinois, 60453, United States

  • Arkansas Children's Hospital

    Little Rock, Arkansas, 72202, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Children's Memorial Hermann Hospital

    Houston, Texas, 77030, United States

  • Children's of Alabama

    Birmingham, Alabama, 35233, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Colorado Children's Hospital

    Aurora, Colorado, 80045, United States

  • Columbia University

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Le Bonheur Children's Hospital

    Memphis, Tennessee, 38103, United States

  • Medical City Dallas

    Dallas, Texas, 75230, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Primary Children's Hospital

    Salt Lake City, Utah, 84113, United States

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • Schneider Children's Medical Center of Israel

    Petah Tikva, Israel

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • St. Joseph's Children's Hospital

    Tampa, Florida, 33607, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • UF Health Shands Hospital

    Gainesville, Florida, 32669, United States

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63130, United States

Conditions

The condition(s) this trial relates to.

pulmonary valve insufficiency tetralogy of fallot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.