Ciusss De L'est De L'île De Montréal

This Canadian study tests a modified version of early post-operative chemotherapy given directly into the abdomen after surgery for peritoneal cancer from colorectal or appendix tumors. The standard treatment takes five days, but this new approach shortens it to two days using a …

This study tests a higher dose of a molecule called UM171 to grow more stem cells from donated cord blood for transplant. It is for adults with high-risk blood cancers like leukemia who have no suitable donor. The goal is to help patients recover blood counts faster, reduce infec…

This pilot study tests whether a home-use device that sends a mild electrical current to the brain (tDCS) can reduce depressive symptoms in people with borderline personality disorder (BPD). Sixty participants will receive either real or sham stimulation twice daily for one week.…

This study tests whether melatonin, a natural sleep hormone, can help treat delirium in intensive care unit (ICU) patients. Delirium is a state of confusion and disorientation common in critically ill people. The trial will give 30 patients either melatonin or a placebo every eve…

This study aims to find the best volume of pain medicine given through an epidural catheter after open abdominal surgery. Sixty adults will receive different doses every hour, and researchers will track how well pain is controlled and if side effects occur. The goal is to improve…

This study will follow 100 women who have had a stem cell transplant to better understand a condition called vulvovaginal chronic graft-versus-host disease (cGVHD). Researchers want to learn how common it is, what symptoms look like, and how it affects sexual health. The goal is …

This study follows 200 adults with advanced chronic kidney disease as they start dialysis, comparing those who choose home dialysis with those who go to a center. Researchers will track quality of life, frailty, fatigue, mood, and thinking skills every 3 to 6 months for a year. T…

This study looks at whether brain activity measured before surgery can predict how much propofol (a common anesthesia drug) a person needs to reach deep anesthesia. Researchers will test 110 adults with cognitive tests and EEG scans before their operation. The goal is to make ane…