Study seeks perfect epidural dose for Post-Surgery pain

NCT ID NCT05534945

Recruiting now Symptom relief Sponsor: Ciusss de L'Est de l'Île de Montréal Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find the best volume of pain medicine given through an epidural catheter after open abdominal surgery. Sixty adults will receive different doses every hour, and researchers will track how well pain is controlled and if side effects occur. The goal is to improve recovery and tailor doses for men and women.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: programmed intermittent epidural bolus (local anesthetic)
What this could lead to: If successful, this could establish the optimal epidural dose for better pain control after abdominal surgery, potentially improving recovery and patient comfort.
What could go wrong: This is a small, early-phase dose-finding study (60 participants) and may not confirm effectiveness or generalizability. Results may vary by individual and do not guarantee improved outcomes.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE POST OPERATIVE PAIN EPIDURAL ANALGESIA LAPAROTOMY

Contacts and locations

Locations

Maisonneuve-Rosemont Hospital
RECRUITING

Montreal, Quebec, H1T2m4, Canada

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