Could a Two-Day chemo boost peritoneal cancer treatment?

NCT ID NCT05913674

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Canadian study tests a modified version of early post-operative chemotherapy given directly into the abdomen after surgery for peritoneal cancer from colorectal or appendix tumors. The standard treatment takes five days, but this new approach shortens it to two days using a continuous infusion of the drug fluorouracil. The trial aims to see if this shorter schedule is easier to complete and safer for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fluorouracil (5-FU) and folinic acid given directly into the abdomen

What this could lead to

If successful, this could make post-surgery chemotherapy simpler and more practical for patients with peritoneal cancer, potentially improving treatment completion rates.

What could go wrong

This is a small, early-phase trial with only 25 participants, so results may not apply broadly. The modified regimen could still cause side effects or prove no better than the standard approach.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

appendiceal neoplasm colorectal cancer peritoneal carcinomatosis peritoneal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Maisonneuve-Rosemont

    RECRUITING

    Montreal, Quebec, H1T 2M4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••