Charles University, Czech Republic

This study is testing how well and how safely an automated insulin delivery system works for adults with type 1 diabetes in everyday life. The system is a patch pump that uses an algorithm to automatically adjust insulin doses. Researchers will follow 200 participants for 24 week…

This study is testing if using a non-invasive magnetic brain stimulator (TMS) right before electroconvulsive therapy (ECT) can make the ECT treatment work with less electrical energy. Researchers want to see if this combination helps people with severe, hard-to-treat depression g…

This study is testing whether a pre-surgery support program helps women with ovarian or endometrial cancer recover better. The program includes exercise, nutritional advice, and psychological support before their operation. Researchers will compare patients who receive this extra…

This study is comparing two surgical methods to repair a bladder prolapse, a condition where the bladder drops into the vagina. It will test a newer, less invasive technique against a standard repair to see which is more effective and safer over one year. The goal is to find the …

This study aims to help people with COPD and asthma stick to their inhaled medication plans. Researchers will test a new mobile app and training program designed to teach both patients and their healthcare providers the correct way to use inhalers. The goal is to improve treatmen…

This study is testing a new type of catheter (a thin, flexible tube) used in a procedure to treat persistent atrial fibrillation, a type of irregular heartbeat. The procedure uses pulsed electrical energy to create small scars in specific areas of the heart to block the faulty el…

This study is testing whether a new video-assisted breathing tube (SaCoVLM™) can help military medics with limited experience safely manage patients' airways. First, medics practice on mannequins, then they use the device on sedated patients during elective surgery. Researchers w…

This study looks back at five years of records from a breast milk bank to learn more about milk donation. Researchers will analyze data from about 500 women who donated milk to see how factors like a mother's age, health, and birth experience relate to how much milk she donates a…

This study aims to understand the long-term recovery of people hospitalized with tick-borne encephalitis (TBE), a serious brain infection from ticks. Researchers will follow 209 children and adults in the Czech Republic for a year after they leave the hospital, checking for lasti…

This study aims to understand how a new type of heart procedure, called pulse field ablation, affects the function of the upper heart chambers in people with a specific type of irregular heartbeat (paroxysmal atrial fibrillation). Researchers will use a special ultrasound camera …