Changhai Hospital

This phase II trial is testing whether adding two immunotherapy drugs (iparomlimab and tuvonralimab) and a targeted therapy (lenvatinib) to standard chemotherapy before surgery can improve outcomes for people with resectable esophageal squamous cell carcinoma. The main goal is to…

This early-phase study tests a new treatment called KN5601, which uses specially engineered natural killer (NK) cells to target and destroy disease-causing immune cells in people with relapsed or refractory IgG4-related disease. The trial will enroll 18 adults and primarily check…

This study tests a new, non-surgical treatment called ERAT for mild appendicitis. Instead of removing the appendix, doctors use a flexible tube through the colon to clear the blockage and infection. The trial will compare ERAT to standard laparoscopic surgery in 376 adults to see…

This study compares two heart procedures for people with paroxysmal atrial fibrillation (AFib), a condition where the heart beats irregularly. One group gets standard ablation to isolate the pulmonary veins, while the other also gets ablation of the superior vena cava using pulse…

This study tests whether spraying a mix of acetic acid and indigo carmine dye during colonoscopy helps doctors find more precancerous polyps (called sessile serrated lesions) in the right side of the colon compared to standard white-light colonoscopy. About 2,689 adults aged 45-8…

This study tests a new device that flattens colon polyps before they are examined under a microscope. The goal is to help doctors better identify sessile serrated lesions, a type of polyp that can lead to colorectal cancer. About 1,156 adults having polyps removed during a colono…

This study looks at whether a special microscope on a thin probe (pCLE) can better detect early stomach cancer than the usual biopsy method. Researchers will review past cases from 169 patients who had both tests. The goal is to see which method is more sensitive and accurate, wh…

This study looks back at medical records of 350 people who had a capsule endoscopy (swallowing a pill-sized camera) for gastrointestinal bleeding. Researchers want to see how often the camera finds the bleeding source and if any problems occur. No new tests or visits are needed—o…

This study compares a new balloon-assisted technique to the standard water-injection method for creating a stomach-to-intestine bypass in people with gastric outlet obstruction. The blockage, often caused by advanced cancer, leads to nausea, vomiting, and malnutrition. The new ap…

This study looks at people who have had certain types of colon polyps (serrated lesions) removed. It aims to find out why some of them later develop new advanced growths in the colon. By tracking 750 adults over time, researchers hope to identify risk factors that could help doct…

This study will follow 800 people, including those with chronic pancreatitis, pancreatic cancer, and healthy volunteers, to learn why some pancreatitis patients later get pancreatic cancer. Participants give blood samples and health info; some may also provide tissue samples. Res…