Changchun Genescience Pharmaceutical Co., Ltd.

This study tests a new drug called GenSci145 in people with advanced solid tumors that have a specific genetic change (PIK3CA mutation). The goal is to see if the drug is safe, how the body processes it, and whether it can shrink tumors. About 186 adults aged 18-75 will take part…

This early-stage study tests a new drug called GenSci098 in people with active thyroid eye disease (TED). The main goal is to see if the drug is safe and tolerable when given as one or multiple injections under the skin. About 76 adults aged 18 to 75 with active TED will take par…

This early-stage study tests a new medicine called GenSci136 in 48 healthy adults in China. The goal is to check if a single shot is safe and how the body processes it. This is a first step toward possibly treating autoimmune diseases, where the immune system attacks the body.

This study tests a new pill called GenSci128 in people whose advanced solid tumors have a specific change in the TP53 gene (Y220C). The main goals are to check the pill's safety, find the best dose, and see if it can shrink tumors. About 82 participants will take the pill by mout…

This study is the first time GenSci143 is being tested in humans. It aims to find out if the drug is safe and can shrink tumors in people with advanced solid cancers that have stopped responding to standard treatments. About 180 adults will take part. The main goals are to check …

This early-stage study tests a new drug called GenSci140 in people with advanced solid tumors that have not responded to other treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 170 adults in China will take part,…

This study tests a new long-acting growth hormone (PEG-rhGH) in children who were born small for their gestational age and remain short. About 72 children will receive either the new drug or standard growth hormone for 26 weeks. The main goal is to see how much they grow in heigh…

This study tests two medicines, cabergoline and bromocriptine, to see which works better at lowering high prolactin levels in women aged 18 to 45. High prolactin can cause irregular periods, breast milk production, and fertility issues. The goal is to bring prolactin back to norm…

This early-stage study tests a single injection of a new drug called GenSci098 in 24 adults with Graves' disease, a condition where the thyroid is overactive. The main goal is to check if the drug is safe and how the body handles it. Participants will be monitored for side effect…

This early-stage study tests a new injection called GenSci134 in healthy adults and in patients with adult growth hormone deficiency. The main goal is to check safety and side effects. The study is currently recruiting 64 participants.

This study tests a new injection called GenSci120 for people with moderate to severe rheumatoid arthritis (RA) who did not get enough relief from standard medications. About 450 adults aged 18-70 will receive either GenSci120, a placebo, or an active comparator over 14 weeks, wit…

This early-stage study tests a new drug called GenSci139 in about 280 people with advanced solid tumors that have spread. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. The study is currently recruiting participants.

This study tests whether a new version of megestrol acetate can help people with advanced lung cancer maintain their appetite and body weight while undergoing chemotherapy and radiation. About 134 participants will receive either the study drug or a placebo alongside standard can…

This study looks at how well a drug called nanocrystalline megestrol acetate works for cancer patients who have cachexia, a condition causing severe weight loss and loss of appetite. About 495 adults with cancer will take the drug, and researchers will check if their appetite and…

This early-stage study tests the safety of a new drug called GS3-007a in 32 healthy Chinese adults aged 18-45. Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through the body. The study also checks if food affects dr…

This study tests whether smoking changes how the body processes a single dose of GS1-144 tablets. It involves 24 healthy Chinese women aged 40-65 who are postmenopausal. Researchers will measure drug levels in the blood to see if smoking affects the drug's breakdown. The goal is …

This early-stage study tests whether a single shot of GenSci161 is safe and how the body processes it. About 44 healthy adults aged 18-45 will take part. No treatment is given—this is purely to gather safety and drug information.