New pill targets hard-to-treat cancers with rare gene mutation

NCT ID NCT06908434

First seen Jan 08, 2026 · Last updated Jun 13, 2026 · Updated 22 times

Summary

This study tests a new pill called GenSci128 in people whose advanced solid tumors have a specific change in the TP53 gene (Y220C). The main goals are to check the pill's safety, find the best dose, and see if it can shrink tumors. About 82 participants will take the pill by mouth, and researchers will monitor side effects and how the drug works in the body.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhongshan Hospital ,Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.