New drug aims to stop weight loss in lung cancer patients during treatment

NCT ID NCT07150663

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether a drug called nanocrystalline megestrol acetate can help people with advanced non-small cell lung cancer maintain their appetite and avoid significant weight loss while undergoing chemoradiotherapy. About 134 participants will receive either the drug or a placebo alongside standard treatment for up to 8 weeks. The goal is to improve quality of life during a tough treatment period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nanocrystalline megestrol acetate

What this could lead to

If it works, this could offer a way to help people with advanced lung cancer maintain their appetite and weight during intensive chemoradiotherapy.

What could go wrong

This is a phase 3 trial, but it focuses on symptom relief, not curing the cancer. The benefits may be modest, and side effects from the drug are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, TongjiMedical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••