Centre Hospitalier Universitaire De Besancon

This study is testing whether adding a new cancer vaccine called UCPVax, with or without an immunotherapy drug (pembrolizumab), can help people live longer with a type of aggressive brain tumor called glioblastoma. It will involve 98 adults who have already had initial surgery an…

This study is checking if it's practical to start a specific heart failure medicine (called a gliflozin) very early, right in the emergency room, for patients aged 75 and older who are hospitalized for a worsening of their condition. It will compare this early start plus a nurse …

This study is testing whether a simple saliva swab can find genetic causes for developmental disorders when standard blood tests have failed. Researchers will use advanced genetic testing on saliva samples from 50 people with neurodevelopmental or intellectual disorders. The goal…

This study aims to see if adding local weather and air pollution information to a doctor's checklist can help emergency rooms spot dangerous aortic tears more quickly. Researchers will look back at the medical records of 580 patients to see if those who had an aortic tear were ex…

This study aims to see if performing an abdominal ultrasound early on helps doctors figure out what is causing severe stomach pain in premature babies. It will enroll 100 premature infants who show signs of serious digestive problems. Researchers will check if the ultrasound imag…

This study is testing whether a tailored exercise program can improve how the body's cells produce energy and reduce depression symptoms in menopausal women. It will compare the exercise program to a non-exercise therapy in 52 women receiving psychiatric care. The main goal is to…

This study aims to understand if a standard blood test used to determine safe chemotherapy doses works correctly for patients who also have kidney problems. Researchers will measure a specific enzyme activity in the blood cells of about 740 patients with breast or digestive cance…

This study aims to test a new ultrasound method called VEXUS to help doctors monitor fluid levels in critically ill patients. Researchers will use ultrasound scans on 525 intensive care patients to see if this method can detect when patients have received too much intravenous flu…