Brown University
Clinical trials sponsored by Brown University, explained in plain language.
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Phone app aims to fight opioid crisis with 24/7 anonymous support
Disease control OngoingThis study is testing whether a mobile app that provides 24/7 access to anonymous, moderated peer support groups can help people recovering from opioid addiction. It aims to help participants build personal recovery resources, stay engaged in treatment, and reduce stress and isol…
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New drug duo aims to stop deadly skin Cancer's return
Disease control OngoingThis study is testing whether a combination of two immunotherapy drugs, nivolumab and ipilimumab, can help prevent melanoma from returning in patients who have had it surgically removed but are at high risk of it coming back. The treatment is given for six months after surgery. T…
Phase: PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Lifeline for heroes: new program aims to stop veteran suicides after hospital
Disease control OngoingThis study is testing if a phone-based support program can help prevent suicide in veterans after they leave a psychiatric hospital. It will enroll 850 veterans at high risk and randomly assign them to either standard care or standard care plus the new support program. Researcher…
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Portable device zaps brain tumors in new melanoma trial
Disease control TerminatedThis study aimed to test the safety and effectiveness of a portable electrical device (NovoTTF-200A) when used together with the immunotherapy drug pembrolizumab for people with melanoma that had spread to the brain. The device, worn like a backpack, delivers low-intensity electr…
Phase: PHASE1, PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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New hope for Tough-to-Treat ovarian cancers: immune therapy trial
Disease control OngoingThis study is testing whether two immunotherapy drugs, nivolumab alone or combined with ipilimumab, can help control recurrent clear cell ovarian, fallopian tube, and related cancers. It will enroll 46 patients whose cancer has returned after standard chemotherapy. The main goal …
Phase: PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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AI steps in to help keep HIV patients on track
Disease control ENROLLING_BY_INVITATIONThis study is testing whether computer algorithms can help HIV clinics in Kenya improve patient care. The algorithms will try to predict which patients are most likely to miss appointments or have their treatment stop working. Clinics that use these predictions will be compared t…
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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New drug combo aims to stop deadly esophageal cancer from coming back
Disease control OngoingThis study tests whether a combination of two drugs (trastuzumab deruxtecan and nivolumab) given for one year after surgery can help prevent cancer from returning in patients with HER2-positive esophageal or gastroesophageal junction cancer. The treatment is for patients who have…
Phase: PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated Mar 11, 2026 14:53 UTC
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Can a school program stop HIV and violence in south african teens?
Prevention OngoingThis study is testing a school-based program called Safe South Africa, designed to prevent HIV and reduce intimate partner violence among teenage boys. The program uses lessons tailored for boys' development to address harmful social norms and behaviors. Researchers are measuring…
Phase: PHASE3 • Sponsor: Brown University • Aim: Prevention
Last updated Mar 23, 2026 15:18 UTC
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New telehealth therapy aims to ease Pandemic's mental toll on LGBTQ+ community
Symptom relief OngoingThis study is testing a brief, online therapy program designed to help LGBTQ+ adults who are experiencing anxiety or depression, particularly due to the social isolation of the COVID-19 pandemic. The program focuses on building social support and coping skills. Researchers are co…
Phase: PHASE2 • Sponsor: Brown University • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Healing harmonies: music prescribed for broken hearts
Symptom relief OngoingThis study is testing whether creating a personalized music playlist can help people process grief after losing a spouse or life partner. Thirty people from a grief support group will talk about their loss and work with a researcher to build a playlist reflecting their emotions. …
Phase: NA • Sponsor: Brown University • Aim: Symptom relief
Last updated Mar 09, 2026 14:25 UTC