Boston Children's Hospital
Clinical trials sponsored by Boston Children's Hospital, explained in plain language.
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Ear drops after tube surgery: do they prevent blockage?
Disease control TerminatedThis study looked at whether using antibiotic ear drops during and after ear tube surgery reduces the chance of tube blockage or ear drainage in children. Only 9 children took part, and each child received drops in one ear but not the other. The study was stopped early, so the fi…
Phase: PHASE4 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Small study tests best epinephrine dose for kids in crisis
Disease control TerminatedThis study compared two different doses of epinephrine (0.5 vs 1.0 mcg/kg) given to children in the intensive care unit for life-threatening low blood pressure. The goal was to see which dose raised blood pressure more effectively. Only 15 children were enrolled before the study …
Phase: PHASE2 • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New pain block for kids after chest surgery shows promise in early study
Symptom relief TerminatedThis study compared two nerve block methods for controlling pain after chest surgery in children and teens. The goal was to see if a newer block (erector spinae) was as good as the standard one (paravertebral) at reducing pain and the need for strong painkillers. The study was st…
Phase: PHASE3 • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New study tests safer pain relief for kids with pancreatitis
Symptom relief TerminatedThis study tested whether using less opioids for initial pain relief in children with acute pancreatitis is as effective and safer than the usual opioid-first approach. It involved 23 children at Boston Children's Hospital. The goal was to gather data for a larger future trial.
Phase: PHASE2 • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Headache after concussion? nerve block study halted early
Symptom relief TerminatedThis study tested whether injecting numbing medication and steroids near nerves in the neck or back of the head could relieve post-traumatic headaches after a concussion or head injury. The trial planned to enroll 16 people aged 14 to 45, but was terminated early, so we don't hav…
Phase: PHASE3 • Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Tiny patients, big questions: how much painkiller reaches the blood?
Knowledge-focused TerminatedThis study looked at how much of the pain medicine ropivacaine gets into the blood of infants and toddlers (0-4 years old) who received a nerve block for pain after chest surgery. The goal was to check if the levels were safe. The study was stopped early and included 26 children.
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC