Axsome Therapeutics, Inc.

This study tested a new migraine medication called AXS-07 (a combination of meloxicam and rizatriptan) in 100 adults whose migraines did not respond well to oral CGRP inhibitors. The goal was to see if the drug could relieve headache pain and the most bothersome symptom without n…

This Phase 3 trial tested whether solriamfetol, a drug already used for sleep disorders, can safely improve mood in adults with major depression. 346 participants received either the drug or a placebo. Researchers measured depression symptoms and side effects to see if this appro…

This study tested a drug called solriamfetol in 516 adults with ADHD to see if it reduces symptoms. Participants took the drug or a placebo for 6 weeks, and researchers measured changes in ADHD symptoms using a standard rating scale. The goal was to find a new treatment option fo…

This study tested a new oral medicine called AXS-07 for quickly stopping migraine headaches in adults. 302 people with migraines took either the study drug or a placebo when their headache started. The goal was to see if the drug could provide pain relief and eliminate the most b…

This study looked at the long-term safety and effectiveness of a drug called AXS-12 for people with narcolepsy who experience sudden muscle weakness (cataplexy) and extreme daytime sleepiness. Researchers followed 68 participants who had already completed an earlier study to see …

This study tested a drug called AXS-05 to see if it is safe and effective for treating agitation in people with Alzheimer's disease over a long period. 456 participants who had already been in earlier studies took the drug, and some later switched to a placebo to see if symptoms …

This study tested an experimental drug called AXS-05 to see if it can safely reduce agitation in people with Alzheimer's disease. Agitation includes restlessness, aggression, and emotional distress. The trial involved 408 participants and compared the drug to a placebo (a dummy p…

This study tested a drug called solriamfetol in 59 adults with obstructive sleep apnea who also had trouble thinking clearly and felt very sleepy during the day. The goal was to see if the drug could improve their attention, processing speed, and overall mental function. Particip…