Akeso

This study tests two experimental drugs, AK146D1 and AK112, given together to people with advanced HER2-negative breast cancer. The goal is to see if the combination is safe and can shrink tumors or slow the disease. About 200 adults aged 18 to 75 will take part.

This study tests a new drug called AK139 in 160 adults with moderate to severe asthma. The goal is to see if it improves lung function and reduces airway inflammation safely. Participants will receive either AK139 or a placebo, and researchers will monitor side effects and immune…

This study tests a new medicine called AK139 for people with moderate to severe atopic dermatitis (eczema). About 168 adults will receive either AK139 or a placebo to see if it safely improves skin symptoms like itching and redness. The trial is in Phase 2 and is not yet recruiti…

This study tests if an immunotherapy drug (AK104) given as a shot under the skin works as well as the same drug given through an IV drip, when both are combined with chemotherapy. About 422 people with advanced stomach or gastroesophageal junction cancer that cannot be removed by…

This study tests two experimental drugs, AK112 and VG2025, given together to people with advanced colorectal cancer that has spread to the liver. The goal is to see if the combination can shrink tumors and control the disease. About 72 adults who have already tried at least one s…

This early-phase study tests a new drug called AK150 in about 96 people with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety and find the right dose. Researchers will also look at how the drug moves through the b…

This early-phase trial tests a new drug called AK138D1, given alone or with another drug (ivonescimab), in 286 people with advanced breast cancer. The main goals are to check safety and see if tumors shrink. Participants must be 18-75, in good enough health, and have at least one…

This study tests a drug called AK112 in 60 adults with advanced non-squamous non-small cell lung cancer who have specific genetic changes and whose previous targeted therapy (TKI) stopped working. The goal is to see if AK112 can shrink tumors or slow the disease. Participants mus…

This early-phase study tests whether AK152 is safe and tolerable in healthy adults and people with Alzheimer's disease. Researchers will also measure how the drug moves through the body and whether it triggers an immune response. The goal is to gather initial safety data before l…

This study tests a new medicine called AK139 for people with moderate to severe seasonal allergic rhinitis (hay fever). About 111 adults aged 18 to 65 will receive either the drug or a placebo to see if it reduces nasal symptoms like sneezing, itching, and congestion. The main go…