WRINKLE

This trial tests a new type of dissolvable thread, called the Demetech Barbed PDO Suture, to see if it can safely reduce wrinkles in the midface (cheek area). About 57 adults with mild to moderate wrinkles will receive the thread, which is designed to lift and smooth the skin ove…

This study tests Restylane Refyne, a hyaluronic acid filler, for treating horizontal neck lines in adults with mild to moderate wrinkles. Each participant receives the filler on one side of the neck with a cannula and on the other side with a needle, allowing a direct comparison.…

This study tests a hyaluronic acid filler called GAL1906 to smooth wrinkles on the décolletage (upper chest). It also checks whether the filler affects how mammograms are read, which is important for breast cancer detection. Participants are women over 21 seeking treatment for ch…

This pilot study tested a micro-coring device on 45 people to see if it can safely reduce wrinkles and skin laxity in the face. The device uses tiny hollow needles to remove small cores of skin, which triggers the body to produce new collagen and elastin. The goal was to improve …

This study tested a gel filler called RHA Redensity Eye to improve moderate to severe under-eye hollows (sunken areas). 248 adults were randomly assigned to receive the filler or no treatment. The main goal was to see if the filler reduced hollow severity after 12 weeks, as rated…

This study compared two hyaluronic acid fillers, Defyne and RHA3, for treating nasolabial folds (smile lines) in 15 adults aged 22 to 65. Each participant received one filler on each side of their face, with an optional touch-up after 4 weeks. Researchers used ultrasound and 3D i…

This completed study tested four topical face care products to see if they could improve facial skin longevity over eight weeks. 132 healthy adults aged 40 to 65 used the products twice daily. Researchers measured skin wrinkles with 3D imaging and asked participants about product…

This completed trial tested the BTL-785F device on 39 healthy adults over 30 who wanted better skin on their face and neck. Participants received three treatments, each lasting 20–60 minutes, spaced 2–6 weeks apart. The goal was to see if the device could improve skin texture, re…