WRINKLE
Clinical trials for WRINKLE explained in plain language.
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New device aims to smooth wrinkles by removing tiny skin cores
Symptom relief CompletedThis pilot study tested a micro-coring device on 45 people to see if it can safely reduce wrinkles and skin laxity in the face. The device uses tiny hollow needles to remove small cores of skin, which triggers the body to produce new collagen and elastin. The goal was to improve …
Matched conditions: WRINKLE
Phase: NA • Sponsor: Cytrellis Biosystems, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New filler shows promise for dark Under-Eye hollows
Symptom relief CompletedThis study tested a gel filler called RHA Redensity Eye to improve moderate to severe under-eye hollows (sunken areas). 248 adults were randomly assigned to receive the filler or no treatment. The main goal was to see if the filler reduced hollow severity after 12 weeks, as rated…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Teoxane SA • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Filler Face-Off: which injectable smooths smile lines best?
Symptom relief CompletedThis study compared two hyaluronic acid fillers, Defyne and RHA3, for treating nasolabial folds (smile lines) in 15 adults aged 22 to 65. Each participant received one filler on each side of their face, with an optional touch-up after 4 weeks. Researchers used ultrasound and 3D i…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Galderma R&D • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Anti-Aging creams put to the test: can they really improve skin longevity?
Symptom relief CompletedThis completed study tested four topical face care products to see if they could improve facial skin longevity over eight weeks. 132 healthy adults aged 40 to 65 used the products twice daily. Researchers measured skin wrinkles with 3D imaging and asked participants about product…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Amazentis SA • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New skin device shows promise for wrinkle and pigment reduction
Symptom relief CompletedThis completed trial tested the BTL-785F device on 39 healthy adults over 30 who wanted better skin on their face and neck. Participants received three treatments, each lasting 20–60 minutes, spaced 2–6 weeks apart. The goal was to see if the device could improve skin texture, re…
Matched conditions: WRINKLE
Phase: NA • Sponsor: BTL Industries Ltd. • Aim: Symptom relief
Last updated Jun 26, 2026 17:30 UTC