WOUNDS AND INJURIES

This study looks at whether giving less intravenous (IV) fluid to critically ill children with traumatic injuries leads to fewer complications. Currently, there is no standard for how much fluid these children should receive. The trial will enroll 250 children aged 6 months to 15…

This study tests a new approach to hand transplantation for people who have lost one or both hands, forearms, or arms. The goal is to help recipients regain hand function and appearance while reducing the need for lifelong, high-dose immune-suppressing drugs that can cause seriou…

This study is testing a new device called WounDx™ that helps surgeons know when a wound is ready to be closed. The device creates a report based on the wound's condition, but the surgeon makes the final decision. About 40 people with large wounds on their arms or legs will take p…

This study looks at whether having healthy meals and shakes delivered to your home for 12 days after orthopedic trauma surgery can improve healing and nutrition. Researchers will check blood markers and wound healing at 2 and 6 weeks after surgery, and follow patients for up to a…

This study tests whether a drug called 4-aminopyridine (4-AP) can help second-degree burns heal faster and with less scarring. About 200 adults with fresh burns will receive the drug or a placebo. The goal is to see if 4-AP improves healing and reduces the need for skin grafts.

This study tests whether a drug called 4-aminopyridine (4-AP) can speed up healing of skin wounds. Researchers will give the drug to 150 healthy adults and measure how quickly small biopsy wounds close. The goal is to find a safe, simple way to help both chronic and acute wounds …

This study tests whether acupuncture can help relieve symptoms of Gulf War Illness, a condition affecting many veterans. Two hundred veterans will receive either biweekly acupuncture for six months or a shorter waitlist followed by weekly sessions. Researchers will measure change…

This study compares a new powder dressing called Altrazeal to standard burn dressings in adults with partial-thickness burns. About 60 people will take part, and researchers will measure pain during dressing changes and track wound healing over 28 days. The goal is to see if the …

This study compares Advanced Trauma Life Support (ATLS) training for doctors against usual care to see if it improves survival in adult trauma patients. Over 4,000 patients from hospitals in India will take part. The goal is to find out if this widely used training actually saves…

This study looks at whether a bedside ultrasound called FAST can safely reduce the need for CT scans in children with blunt belly injuries. About 4,300 children will be randomly assigned to get either a FAST exam or standard care. The goal is to see if FAST can spot serious injur…

This study aims to see if doctors can change normal skin into the thicker, tougher skin found on palms and soles. Researchers will take a small skin sample, grow the cells in a lab, and inject them back into the skin. The goal is to measure changes in skin thickness and firmness.…

This study aims to create a smart computer program that helps doctors better understand the sounds from a handheld device used to check blood flow in arteries. Many doctors lack formal training in using this device, which can lead to missed or wrong diagnoses. The study will coll…