URINARY BLADDER NEOPLASMS

This phase 2 trial tested a combination of two drugs—TAR-200 (placed directly into the bladder) and cetrelimab (an immunotherapy given by IV)—in 163 people with muscle-invasive bladder cancer who were scheduled for bladder removal surgery and could not or would not take standard …

This early-phase trial tested two drugs—durvalumab and vicineum—in 15 people with high-grade non-muscle-invasive bladder cancer that had not responded to standard BCG treatment. The goal was to see if the combination is safe and can help the immune system fight the cancer. Partic…

This phase 2 trial tested a daily pill called erdafitinib against standard chemotherapy for people with a high-risk bladder cancer that returned after BCG treatment. The study enrolled 107 participants whose tumors have specific FGFR gene changes. The goal was to see if erdafitin…

This study tested two surgical methods for removing early-stage bladder tumors that haven't spread to muscle. One method removes the tumor in one piece (en bloc), while the standard method removes it in multiple pieces. Researchers wanted to see if the one-piece method gives bett…

This study tested whether a simple urine test (Xpert Bladder Cancer Detection Test) can accurately detect bladder cancer in people undergoing cystoscopy. Researchers enrolled 127 adults in Greenland, where access to urology services is limited. The goal was to see if the urine te…

This early-phase trial tested whether a nutritional supplement called Impact Advanced Recovery® could help men recover better after bladder cancer surgery. Thirty men took the drink before and after their operation. The goal was to see if it reduced surgical complications, infect…

This study tested a health cloud platform accessed via smartphone to help patients who have a urostomy after bladder cancer surgery. The platform allowed patients to check their medical info and communicate with nurses. Researchers measured whether this improved patients' ability…