TOBACCO SMOKING
Clinical trials for TOBACCO SMOKING explained in plain language.
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New study explores e-cigarettes and nicotine patches to help HIV patients quit smoking
Disease control CompletedThis study tested two methods to help people living with HIV/AIDS in South Africa reduce their cigarette smoking: using e-cigarettes or nicotine replacement therapy (like patches), plus supportive text messages. 106 adults who smoked daily took part. The goal was to see if these …
Matched conditions: TOBACCO SMOKING
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New program aims to help FDNY firefighters kick the habit for good
Disease control CompletedThis study tested an enhanced tobacco cessation program for retired FDNY firefighters who smoke. The program automatically enrolled participants in counseling, tailored the advice based on their lung scans and breathing tests, and started a quit-smoking medication (varenicline) e…
Matched conditions: TOBACCO SMOKING
Phase: PHASE4 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can an iPad avatar help you quit smoking?
Disease control CompletedThis study tested a computer program called C-Raven that uses an interactive avatar to help people quit smoking. Participants used an iPad for two 20-minute sessions and could get nicotine replacement therapy and support from a community health worker. The study was small (18 peo…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Cash for quitters: homeless smokers get paid to stay smoke-free
Disease control CompletedThis study tested whether offering financial rewards for staying smoke-free helps homeless smokers quit. 184 participants received varenicline (Chantix) and coaching, with some also getting escalating cash rewards for passing saliva tests. The goal was to see if incentives boost …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Could taking chantix for a month before quitting boost success rates?
Disease control CompletedThis study tested whether taking varenicline (Chantix) for four weeks before quitting smoking, instead of the standard one week, helps more people stay smoke-free. 320 smokers were randomly assigned to either the extended or standard pre-quit schedule, along with counseling. The …
Matched conditions: TOBACCO SMOKING
Phase: PHASE3 • Sponsor: State University of New York at Buffalo • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Guam school curriculum aims to curb teen vaping and betel nut use
Prevention CompletedThis study tested a school-based curriculum designed to prevent e-cigarette, tobacco, and betel (areca) nut use among middle school students in Guam. Over 500 students from public schools participated, with some schools receiving the new curriculum and others continuing standard …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: University of Guam • Aim: Prevention
Last updated Jun 27, 2026 12:30 UTC
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Free samples of Quit-Smoking drugs mailed to your door: does it work?
Symptom relief CompletedThis study tested whether mailing free samples of varenicline (Chantix) or nicotine patches and lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a one-time sample of varenicline, nicotine replacement products, or no medication. Participants were no…
Matched conditions: TOBACCO SMOKING
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New program aims to help HIV patients kick the habit while in hospital
Symptom relief CompletedThis pilot study tested a program for hospitalized people with HIV who smoke. Participants received two computer counseling sessions, nicotine replacement therapy, and follow-up support from a community health worker for up to 8 weeks. The goal was to see if this approach is feas…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Brain zaps may curb smoking cravings in HIV patients
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique called TMS could reduce smoking cravings and attention to cigarette cues in people living with HIV/AIDS. Four participants received either real or sham TMS sessions. The goal was to see if TMS could help them fo…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Gopalkumar Rakesh • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Menthol ban study: will smokers switch or quit?
Knowledge-focused CompletedThis study tested how a menthol ban in cigarettes and e-cigarettes affects people who currently smoke menthol cigarettes. 151 adult smokers were asked to try different scenarios, like a ban on menthol cigarettes only or a total ban on menthol flavors. The goal was to see if they …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Could sedatives help smokers quit? early study tests the idea
Knowledge-focused CompletedThis small, early-phase study tested whether a single dose of sedatives like ketamine, midazolam, or dexmedetomidine could reduce cigarette cravings and smoking in 20 daily smokers. Participants received one of these drugs or a placebo (saline) and reported their cravings, withdr…
Matched conditions: TOBACCO SMOKING
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Heated tobacco vs. cigarettes: which pollutes the air less?
Knowledge-focused CompletedThis study measured harmful chemicals in the air after adults used either a heated tobacco product (ploom) or regular cigarettes in a sealed room. Researchers tracked over 20 pollutants like nicotine, formaldehyde, and benzene. The goal was to see how the two products differ in s…
Matched conditions: TOBACCO SMOKING
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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JUUL vs. cigarettes: which delivers nicotine faster?
Knowledge-focused CompletedThis study looked at how nicotine enters the body when people use JUUL e-cigarettes compared to smoking regular tobacco cigarettes. Seventeen healthy adult smokers took part, and researchers measured nicotine levels and heart rate after each product. The goal was to understand th…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Training clinic staff to help patients quit smoking shows promise
Knowledge-focused CompletedThis study tested whether training, coaching, and strategy meetings help community mental health clinic staff deliver better smoking cessation support. Researchers worked with 91 staff members from multiple clinics. The goal was to see if staff knowledge and confidence in helping…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:33 UTC