TIBIAL PLATEAU FRACTURE
Clinical trials for TIBIAL PLATEAU FRACTURE explained in plain language.
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Can a second antibiotic powder slash infection risk in severe fractures?
Disease control CompletedThis study tested whether adding tobramycin powder to the standard vancomycin powder in the wound during surgery reduces infections after high-risk leg fracture repair. About 1,550 adults with tibial plateau or pilon fractures at high infection risk took part. The main goal was t…
Matched conditions: TIBIAL PLATEAU FRACTURE
Phase: PHASE3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Antibiotic powder sprinkled in wounds may cut infection risk after severe leg fractures
Disease control CompletedThis trial investigates whether placing vancomycin antibiotic powder directly into the wound during surgery can reduce deep surgical site infections in people with severe tibial plateau fractures. Participants are adults with high-energy fractures requiring plate and screw fixati…
Matched conditions: TIBIAL PLATEAU FRACTURE
Phase: PHASE3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Extra oxygen during surgery may cut infection risk after bad breaks
Disease control CompletedThis study tested whether giving patients extra oxygen (80% FiO2) during surgery could reduce surgical site infections after severe tibial plateau or pilon fractures. Over 1,100 patients were randomly assigned to receive either supplemental oxygen or standard care. The main goal …
Matched conditions: TIBIAL PLATEAU FRACTURE
Phase: NA • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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MRI scans reveal hidden clues in complex knee fractures
Knowledge-focused CompletedThis study looked at 77 adults with a specific type of knee fracture (Schatzker IV) to see if MRI and CT scans could predict which fractures also involve a dislocation. Researchers compared imaging features between those with and without dislocation. The goal was to help surgeons…
Matched conditions: TIBIAL PLATEAU FRACTURE
Sponsor: Second Affiliated Hospital of Soochow University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Smart crutches could boost fracture recovery
Knowledge-focused CompletedThis study tested whether crutches that give feedback to patients help them follow doctor's orders about how much weight to put on their healing leg. Twenty people with certain types of leg fractures used either regular crutches or smart crutches that tracked their weight-bearing…
Matched conditions: TIBIAL PLATEAU FRACTURE
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New toolkit tracks walking recovery after leg breaks
Knowledge-focused CompletedThis study tested a new 'Mobility Toolkit' to see how well it measures walking recovery in 244 adults aged 18-60 who had surgery for serious leg fractures. Participants used the toolkit during clinic visits over a year. The goal was to see if the toolkit is easy to use and accura…
Matched conditions: TIBIAL PLATEAU FRACTURE
Sponsor: Major Extremity Trauma Research Consortium • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC