TAKAYASU ARTERITIS

This study tests whether a live attenuated dengue vaccine (Butantan-DV) is safe and works well in people aged 12–59 with autoimmune rheumatic diseases like rheumatoid arthritis or lupus, who are stable on low or no immune-suppressing drugs. Participants receive one shot and are m…

This study tests whether two drugs, dapagliflozin and bosentan, can improve blood vessel function in people with large vessel vasculitis (LVV), a condition that raises the risk of heart attacks and strokes. About 60 adults with stable LVV will take both drugs for 6 weeks, then da…

This study looks at whether people with Takayasu arteritis, a rare blood vessel disease, can safely stop taking biologic medications after being in remission for a long time. About 40 participants who have been on biologics for at least 3 years and have no active disease will slo…

This study uses two questionnaires to learn about the experiences of people with Takayasu arteritis and how doctors manage the condition. About 50 patients and an unspecified number of physicians will share their views on symptoms, treatment priorities, and unmet needs. The goal …

This study looks at how two rare diseases that cause blood vessel inflammation—Takayasu arteritis and Behçet's disease—affect physical strength, breathing, daily function, and emotional well-being. Researchers will compare 30 participants (patients and healthy volunteers) using s…

This study aims to learn how well heart scans (MRI, ultrasound, PET) can detect and predict outcomes in people with suspected or known inflammatory heart diseases. Researchers will follow 5,000 adults for one year to see how often heart involvement is confirmed and how it affects…

This study gathers existing tissue samples from 1,000 people with various forms of vasculitis, a group of rare diseases that cause blood vessel inflammation. Researchers will analyze the tissue alongside medical data to find genes linked to the disease. The goal is to better unde…