New drug combo aims to shield vasculitis patients from heart attacks and strokes

NCT ID NCT06887062

First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 24 times

Summary

This study tests whether two drugs, dapagliflozin and bosentan, can improve blood vessel function in people with large vessel vasculitis (LVV), a condition that raises the risk of heart attacks and strokes. About 60 adults with stable LVV will take both drugs for 6 weeks, then dapagliflozin alone for 4 more weeks. The goal is to see if these treatments can reduce blood vessel stiffness and lower blood pressure.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Edinburgh

    RECRUITING

    Edinburgh, EH16 4TJ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.