SYSTEMIC SCLEROSIS (SSC)

This study is testing whether a single-dose dengue vaccine is safe and works well for people with autoimmune diseases like rheumatoid arthritis or lupus. Researchers will compare about 320 patients with these conditions to 160 healthy volunteers, all living in areas where dengue …

This is an early safety study testing a new drug called GB261 in people with systemic sclerosis, a condition that causes skin and organ hardening. The study will enroll 10 adults who have had the disease for 7 years or less and haven't responded well to other treatments. Research…

This is a very early study to check if a new drug called cizutamig is safe and how it behaves in the body of people with systemic sclerosis. It will involve 10 adults with a specific, more severe form of the disease who haven't responded well to other treatments. The main goal is…

This early-stage study is testing a new cell therapy called BCT301 for people with severe autoimmune diseases that haven't responded to standard treatments. The therapy uses lab-made immune cells designed to target and remove harmful B cells, which are thought to drive these dise…

This early-stage study is testing an experimental treatment called QEL-005 in adults with two severe autoimmune conditions: difficult-to-treat rheumatoid arthritis and a serious form of systemic sclerosis. The treatment involves taking a patient's own immune cells, modifying them…

This study aims to understand how different immune cells in the blood are related to disease activity in people with various autoimmune conditions. Researchers will analyze blood samples from 500 participants, including people with diseases like lupus and rheumatoid arthritis, as…

This study aims to understand if a protein in the blood (called FAP) can tell doctors about disease activity and lung scarring in rheumatoid arthritis and systemic sclerosis (scleroderma). Researchers will take a single blood sample from 111 people (patients and healthy volunteer…