SYNOVIAL SARCOMA
Clinical trials for SYNOVIAL SARCOMA explained in plain language.
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Engineered immune cells take on childhood cancers in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a protein called B…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 17, 2026 01:59 UTC
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Supercharged immune cells take aim at multiple cancer types in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for people with certain advanced cancers (bladder, melanoma, head/neck, ovarian, lung, esophageal, stomach, sarcoma) that carry a protein called MAGE-A4. Patients' own immune cells are genetically modified to recognize and …
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE1 • Sponsor: USWM CT, LLC • Aim: Disease control
Last updated May 17, 2026 01:47 UTC
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Supercharged immune cells take on rare sarcomas
Disease control OngoingThis study tests a new treatment called ADP-A2M4 for people with advanced synovial sarcoma or myxoid liposarcoma that has spread or cannot be removed by surgery. The treatment uses a patient's own immune cells that are genetically modified to recognize and attack cancer cells. Th…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE2 • Sponsor: USWM CT, LLC • Aim: Disease control
Last updated May 17, 2026 01:47 UTC
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Immunotherapy duo shows promise in early sarcoma trial
Disease control OngoingThis early-phase study tests whether adding an experimental drug (BO-112) to the immunotherapy nivolumab before surgery can help treat soft tissue sarcoma. About 14 adults with removable tumors will receive the combination to check for side effects and immune changes. The goal is…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 01:46 UTC
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Genetically modified immune cells take on Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a treatment called TBI-1301 for people with advanced solid tumors (like sarcoma, melanoma, or ovarian cancer) that have not responded to other therapies. The treatment uses a patient's own immune cells, which are genetically modified in a lab to bette…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 17, 2026 01:46 UTC
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New combo therapy aims to shrink sarcomas before surgery
Disease control OngoingThis study looks at whether adding the drug pazopanib to standard radiation or chemoradiation helps shrink soft tissue sarcomas before they are removed surgically. About 140 adults and children with newly diagnosed, high-risk sarcomas that can be operated on are participating. Th…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Engineered immune cells take aim at childhood cancers in early trial
Disease control OngoingThis early-stage study tests a personalized cell therapy for children and young adults (ages 1–30) with solid tumors that have come back or not responded to treatment. The therapy uses the patient's own immune cells, modified to recognize and attack tumors that carry a protein ca…
Matched conditions: SYNOVIAL SARCOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 16:00 UTC