STROKE, ISCHEMIC

This study tests a new biodegradable device to close a patent foramen ovale (PFO), a small hole in the heart that can cause strokes. About 258 people aged 18-65 who have had a stroke or TIA linked to a PFO will receive the device. The goal is to see if it safely and effectively s…

This study tests whether the drug tirofiban can help people who had a stroke more than 24 hours ago but within 7 days. It uses a special MRI scan to pick the right patients. About 458 adults will take part to see if the drug improves recovery without causing serious bleeding.

This study tests whether a new MRI-based method (IMPROVE) can better identify which patients with narrowed carotid arteries need surgery or stenting to prevent a future stroke. About 613 adults who recently had a minor stroke or TIA will be randomly assigned to the new method or …

This study compares Vojta therapy, a movement-based treatment, to standard care for helping people recover after an ischemic stroke. Researchers want to see if Vojta therapy improves trunk control and daily living skills better than usual therapy. The study plans to enroll 150 ad…

This study will check if a non-invasive device can accurately detect high pressure inside the skull in 300 adults with traumatic brain injury or stroke. The device uses a sensor placed on the head to measure brain pressure waves. If successful, it could help doctors make faster d…

This study tests whether adding a very low dose of the blood thinner edoxaban (15 mg daily) to standard aspirin or clopidogrel therapy can reduce the risk of another stroke in people aged 75 and older who have already had an ischemic stroke. About 1,200 participants will be rando…

This study tests a 6-week rehabilitation program for one person who had a stroke more than 6 months ago. The program combines special exercises, ultrasound, and hand therapy devices to improve movement and daily living skills. The goal is to see if these methods help with recover…

This study tests whether an artificial intelligence system can help therapists create personalized robotic rehab programs for people who had a stroke within the last six months. One hundred participants will either get AI-guided robotic therapy or standard therapist-guided roboti…

This study tests whether listening to music for 30 minutes each day can improve attention, language, and quality of life in people with aphasia after a stroke. 45 adults who had a stroke at least 6 months ago will be assigned to listen to music, an audiobook, or no intervention f…

This pilot study tests a new, faster MRI technique called MR fingerprinting for people who have had an ischemic stroke. Standard MRI scans take 20-25 minutes, but every minute counts in stroke care. The study will enroll 10 adults with a recent stroke to see if the new method can…