STAGE IV RENAL CELL CANCER AJCC V8
Clinical trials for STAGE IV RENAL CELL CANCER AJCC V8 explained in plain language.
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New drug combo shows promise in shrinking kidney tumors before surgery
Disease control TerminatedThis study tested whether giving pembrolizumab (an immunotherapy) with or without axitinib (a targeted drug) before surgery helps control advanced kidney cancer. Six participants with clear cell kidney cancer that had spread were enrolled. The goal was to see if the treatment boo…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 15, 2026 19:09 UTC
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Immunotherapy combo shows promise in rare kidney cancer trial
Disease control TerminatedThis study tested two immunotherapy drugs, nivolumab and ipilimumab, in 10 people with a rare and aggressive kidney cancer called renal medullary carcinoma. The goal was to see if the combination could shrink tumors or stop them from growing. The trial was stopped early, but the …
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combo could shrink tumors or con…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Brain radiation showdown: whole brain vs. targeted beams for recurrent tumors
Disease control TerminatedThis study looked at two radiation approaches for people whose cancer has spread to the brain and come back after initial treatment. One approach uses targeted radiation only on the new spots, while the other uses whole-brain radiation that tries to protect memory areas and inclu…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 09, 2026 12:07 UTC
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New drug combo tested for advanced kidney cancer shows promise but study halted early
Disease control TerminatedThis study tested a combination of two drugs, sitravatinib and nivolumab, in people with advanced kidney cancer that had spread and worsened after prior treatment. The goal was to see if the combination could shrink tumors or slow the disease. The study was stopped early after en…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 01, 2026 18:01 UTC