New drug combo tested for advanced kidney cancer shows promise but study halted early

NCT ID NCT04904302

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a combination of two drugs, sitravatinib and nivolumab, in people with advanced kidney cancer that had spread and worsened after prior treatment. The goal was to see if the combination could shrink tumors or slow the disease. The study was stopped early after enrolling only 15 participants, so results are limited.

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Conditions

The condition(s) this trial relates to.

clear cell renal carcinoma Clear-cell metastatic renal cell carcinoma renal cell adenocarcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Indiana University Hospital / IU Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States