SPINAL CORD INJURIES

This trial tests whether adding robotic rehabilitation devices to standard physiotherapy can improve arm and leg function in adults with movement problems from stroke, spinal cord injury, traumatic brain injury, or orthopedic surgery. Participants will receive robotic-assisted se…

This trial tests whether testosterone therapy can help men with spinal cord injury who have low testosterone and difficulty walking. The goal is to see if it increases muscle and bone in the legs, reduces body fat, and improves strength. Some participants also receive finasteride…

This study tests whether a robotic device called ZEPU-AI3 can safely help people with lower limb weakness from stroke, spinal cord injury, or orthopedic surgery improve their walking. Participants receive either standard rehabilitation alone or standard rehab plus robot-assisted …

This trial investigates whether combining high-frequency magnetic stimulation of the sacral nerve roots with ultrasound therapy to the bladder can reduce involuntary bladder contractions in people with spinal cord injury. Participants receive daily treatments for three weeks, and…

This study explores whether applying mild electrical stimulation to the spinal cord through the skin can improve blood pressure control in people with spinal cord injury. Participants will undergo tilt-table tests to measure immediate effects, plus 20 stimulation sessions to see …

This study tests whether a drug called istradefylline can boost the walking improvements seen with low-oxygen therapy in people with chronic, incomplete spinal cord injury. About 40 adults aged 18-75 with injuries at least one year old will receive the drug or a placebo before wa…

This phase 2 trial tests whether a nitric oxide spray (glyceryl trinitrate) can prevent dangerous blood pressure spikes during bowel care in people with spinal cord injury. 26 participants will receive either the active spray or a placebo during two at-home bowel care sessions. T…

This trial compares two adaptive indoor rowing seats designed for Veterans who have limited trunk stability due to spinal cord injury, stroke, or neurodegenerative conditions. Participants will try both seats during short rowing sessions, and researchers will measure trunk moveme…

This study will develop and test a new digital pain rehabilitation program for people with spinal cord injury (SCI) who have chronic pain. The program is based on a biopsychosocial model, which looks at physical, emotional, and social factors. The study will enroll 32 adults who …

This study looks at 40 veterans with chronic spinal cord injury to find any remaining nerve connections below their injury. Researchers will use MRI scans and non-invasive stimulation to measure these connections. The goal is to understand who might benefit from future treatments…

This pilot study will test whether temporarily stimulating nerves in the lower spine can improve movement and bladder function in one person with a spinal cord injury. The participant will have small electrodes placed near the spinal nerves and undergo 10 days of rehabilitation s…

This observational study will look at how fear of movement (kinesiophobia) relates to independence, fear of falling, pain, and mood in 70 adults with paraplegic spinal cord injury. Participants will fill out questionnaires during one visit. The goal is to better understand these …

This study looks at how quickly people with paraplegic spinal cord injury can mentally picture moving their hands or feet compared to healthy individuals. Researchers will use a computer task where participants identify left or right hand/foot images. The goal is to understand ho…