SOLID TUMOURS

This is the first human study of an experimental cancer drug called AP601. Researchers will test increasing doses in 36 patients with advanced solid tumors to find the highest safe amount. The main goal is to understand the drug's safety and how the body processes it, while also …

This early-stage trial is testing a new cancer drug called BMS-986517 in adults with advanced solid tumors that have spread or cannot be surgically removed. The main goals are to determine if the drug is safe, what side effects it causes, and what dose works best. Researchers wil…

This is the first human study of an experimental oral medication called ODM-212 for people with advanced solid tumors that have stopped responding to standard treatments. The trial will test the drug's safety, determine the right dose, and see if it shows any anti-cancer activity…

This is a first-in-human study to test the safety of a new drug called RC220 when given with the common chemotherapy drug doxorubicin. It will involve about 53 adults with advanced solid tumors who may benefit from anthracycline treatment. The main goals are to find the safest do…

This trial is testing if an existing immunotherapy drug called atezolizumab can help control rare cancers or common cancers with rare genetic features. It will involve about 30 adults and children whose cancers have specific genetic markers. The goal is to see if this approved dr…

This is a first-in-human study to test the safety and find the right dose of a new oral drug, OKN4395, for people with advanced solid tumors. The trial will give the drug alone and combined with an existing immunotherapy (pembrolizumab) to about 166 participants with cancers like…

This study is testing whether a daily pill called zongertinib can help control advanced cancers that have specific changes in a protein called HER2. It is for adults whose cancer has continued to grow despite previous treatments. Doctors will check if the medicine shrinks tumors …

This study is analyzing existing research to find the best dose of the drug olanzapine for preventing severe nausea and vomiting caused by strong chemotherapy. It compares three doses (2.5mg, 5mg, and 10mg) to see if lower doses work as well as the standard 10mg dose but cause le…

This study is creating a large registry to collect information from 15,000 adults with solid tumor cancers. It aims to understand how detailed genetic testing results relate to the treatments patients receive and their long-term survival. The goal is to gather real-world evidence…

This study aims to understand why cancer spreads and stops responding to treatment. Researchers will collect leftover tumor and blood samples from up to 3,000 patients over time. By analyzing these samples with advanced lab tests, they hope to discover clues that could lead to mo…