New hope for Hard-to-Treat cancers? early trial launches

NCT ID NCT07160725

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing a new drug called BMS-986517 in about 315 adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goal is to check the drug's safety and find the right dose. Researchers will also look for signs that the drug shrinks tumors. This is a first-in-human study, so the drug's effects are not yet known.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BMS-986517

What this could lead to

If successful, this could point toward a new treatment option for certain advanced solid tumors that have not responded to other therapies.

What could go wrong

This is a very early, first-in-human study focused mainly on safety. It is small and may not show enough benefit to move forward. Side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma hormone receptor-positive breast cancer non-small cell lung carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Clinica Universidad de Navarra

    RECRUITING

    Pamplona, Navarre, 31008, Spain

    Contact Phone: •••-•••-••••

  • Copenhagen University Hospital Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-••••

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-••••

  • Herlev and Gentofte Hospital

    RECRUITING

    Copenhagen, Capital Region, 2730, Denmark

    Contact Phone: •••-•••-••••

  • Hospital Universitario Fundación Jiménez Díaz

    RECRUITING

    Madrid, 28040, Spain

    Contact Phone: •••-•••-••••

  • Local Institution - 0022

    NOT_YET_RECRUITING

    Badalona, Barcelona [Barcelona], 08916, Spain

    Contact

  • Local Institution - 0023

    NOT_YET_RECRUITING

    Madrid, 28050, Spain

    Contact

  • Local Institution - 0024

    NOT_YET_RECRUITING

    Barcelona, Barcelona [Barcelona], 08035, Spain

    Contact

  • Local Institution - 0026

    NOT_YET_RECRUITING

    Málaga, Andalusia, 29010, Spain

    Contact

  • Local Institution - 0033

    NOT_YET_RECRUITING

    Irvine, California, 92612, United States

    Contact

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, 104-0045, Japan

    Contact Phone: •••-•••-••••

  • Odense Universitetshospital

    RECRUITING

    Odense, Region Syddanmark, 5000, Denmark

    Contact Phone: •••-•••-••••

  • START - Dallas Fort Worth

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-••••

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Phone: •••-•••-••••

  • START San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-••••

  • Sanford Cancer Center

    RECRUITING

    Sioux Falls, South Dakota, 57104, United States

    Contact Phone: •••-•••-••••

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-••••

  • USC/Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-••••

  • University of California, Irvine (UCI) Health - UC Irvine Medical Center

    RECRUITING

    Orange, California, 92868-3201, United States

    Contact Phone: •••-•••-••••