Could a simple shot replace IV drips for this cancer drug?

NCT ID NCT07391670

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 14, 2026 · Updated 4 times

Summary

This early-stage trial is testing whether giving durvalumab as a shot under the skin works as well as the standard IV infusion. About 40 adults with various solid tumours will receive the injection, and researchers will measure drug levels in the blood and watch for side effects. If successful, it could make treatment faster and more convenient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: durvalumab (an immunotherapy drug) given as a shot under the skin
What this could lead to: If it works, this could offer a faster, more convenient way to give durvalumab without needing an IV line.
What could go wrong: This is a very early phase 1 trial with only 40 people, so it is not yet clear if the shot works as well as the IV version. Side effects from the injection or the drug itself are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma non-small cell lung carcinoma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOURS

Contacts and locations

Locations

Research Site
NOT_YET_RECRUITING

Fitzroy, 3065, Australia
Research Site
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St Albans, 3021, Australia
Research Site
NOT_YET_RECRUITING

Woolloongabba, 4102, Australia
Research Site
RECRUITING

Batumi, 6010, Georgia
Research Site
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Tbilisi, 0112, Georgia
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Tbilisi, 0114, Georgia
Research Site
RECRUITING

Brzozów, 36-200, Poland
Research Site
NOT_YET_RECRUITING

Koszalin, 75-581, Poland
Research Site
RECRUITING

Lublin, 20-090, Poland
Research Site
RECRUITING

Olsztyn, 10-357, Poland
Research Site
RECRUITING

Przemyśl, 37-700, Poland
Research Site
RECRUITING

Seongnam-si, 13620, South Korea
Research Site
RECRUITING

Seoul, 03722, South Korea
Research Site
RECRUITING

Seoul, 06351, South Korea
Research Site
RECRUITING

Seoul, 5505, South Korea
Research Site
RECRUITING

Tainan, 73657, Taiwan
Research Site
RECRUITING

Taipei, 110, Taiwan
Research Site
NOT_YET_RECRUITING

Taipei, 112, Taiwan
Research Site
NOT_YET_RECRUITING

Taoyuan, 333, Taiwan

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