SLEEP APNEA

This study looks at whether using a CPAP machine to treat sleep apnea shortly after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. About 3,000 adults who had a stroke and have sleep apnea will take part. The goal is to see if thi…

This study checks if a Withings smartwatch can accurately spot sleep apnea by tracking movement, heart rate, breathing, and blood oxygen. About 220 adults who already need a sleep lab test will wear the watch overnight. If it works well, it could help millions of undiagnosed peop…

This study looks at whether adding CPAP (a machine that helps you breathe at night) to a healthy lifestyle program can lower the risk of diabetes in people with prediabetes and sleep apnea. About 174 overweight or obese adults with both conditions will be followed for 6 months. T…

This study looks at whether showing sleep apnea patients how their CPAP machine use compares to other patients helps them use it more regularly. About 186 adults who have been on CPAP for at least three months will be randomly assigned to get either their own usage data or their …

This study tests three different drugs—sivopixant, acetazolamide, and SASS-001—to see if they can reduce the number of breathing pauses (apneas) in adults with sleep apnea that involves a central (brain-related) component. About 60 participants with certain heart conditions will …

This study will observe 100 adults with sleep bruxism (teeth grinding during sleep) to understand how it relates to sleep quality, heart health, thyroid function, jaw muscle function, and emotional well-being. Participants will undergo sleep monitoring and questionnaires. No trea…

This study collects blood, urine, and tissue samples from 500 adults with obesity (BMI 30 or higher) who are undergoing weight-loss treatment or have had bariatric surgery. Researchers will store these samples for up to 10 years to study why people gain or lose weight, why some t…

This study looks at why overweight adults with sleep apnea have a higher risk of blood sugar problems and diabetes. Researchers will compare people with and without sleep apnea, and test whether using a CPAP machine or just extra oxygen at night can improve how the body handles s…

This study aimed to test a new wearable device that monitors central sleep apnea (pauses in breathing during sleep) in infants and children up to 5 years old. The device was to be worn around the abdomen overnight alongside standard monitoring equipment. The goal was to see how a…

This study looks at whether dopamine levels and certain genes are linked to sleep breathing disorders like sleep apnea. About 100 adults with suspected sleep issues will have an overnight sleep test and a blood draw. The goal is to understand the connection, not to test a treatme…

This study looks at how normal age-related sleep changes and sleep apnea might increase the risk of Alzheimer's disease in healthy older adults. Researchers will monitor sleep and brain amyloid levels in 158 people aged 55-75 over two years. The goal is to find ways to prevent Al…

This study uses a 30-40 minute online survey to understand how being on call affects the sleep of 1000 medical trainees (students, residents, fellows). It asks about sleep habits, knowledge, and uses standard questionnaires to measure sleepiness and insomnia. The goal is to gathe…

This study looks at how sleep apnea might contribute to the development of pre-diabetes in overweight or obese adults. Researchers will measure stress hormones in the blood to understand the connection. The goal is to learn more about the early steps that lead to diabetes, not to…

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …