New drug combo aims to quiet nighttime breathing pauses
NCT ID NCT06776432
First seen Nov 01, 2025 · Last updated Jun 09, 2026 · Updated 32 times
Summary
This study tests three different drugs—sivopixant, acetazolamide, and SASS-001—to see if they can reduce the number of breathing pauses (apneas) in adults with sleep apnea that involves a central (brain-related) component. About 60 participants with certain heart conditions will receive one of the drugs or a placebo. The main goal is to measure changes in breathing pauses during sleep after treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Altman Clinical and Translational Research Institute (ACTRI)
La Jolla, California, 92037, United States
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Huntsville Research Institute LLC
Huntsville, Texas, 77340, United States
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Infinity Medical Research
North Dartmouth, Massachusetts, 02747, United States
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Intrepid Research, LLC
Cincinnati, Ohio, 45245, United States
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John D. Dingell VA Medical Center
Detroit, Michigan, 48201, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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OnSite Clinical Solutions
Rock Hill, South Carolina, 29732, United States
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PharmaDev Clinical Research Institute, LLC
Miami, Florida, 33176, United States
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Teradan Clinical Trials
Brandon, Florida, 33511, United States
Conditions
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