SJOGREN'S SYNDROME
Clinical trials for SJOGREN'S SYNDROME explained in plain language.
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New drug shows promise for Sjögren's sufferers in major trial
Disease control OngoingThis study tests an investigational drug called dazodalibep in 651 adults with Sjögren's syndrome who have moderate-to-severe disease activity. The goal is to see if the drug can reduce overall disease activity and improve symptoms like dryness, compared to a placebo. Participant…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE3 • Sponsor: Amgen • Aim: Disease control
Last updated May 17, 2026 05:09 UTC
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Engineered immune cells take on lupus and scleroderma in new trial
Disease control TerminatedThis early-stage study is testing a new treatment called RD06-04, which uses a patient's own immune cells modified to target and attack faulty B cells. The goal is to see if it is safe and tolerable for people with active autoimmune diseases like lupus, scleroderma, and Sjögren's…
Matched conditions: SJOGREN'S SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Nanjing Bioheng Biotech Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 05:03 UTC
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New drug tofacitinib tested for Sjogren's safety
Disease control OngoingThis study tested the safety of an oral drug called tofacitinib in 23 adults with mild-to-moderate Sjogren's syndrome, an autoimmune disease. Participants took the drug or a placebo daily for 168 days and were monitored for side effects. The goal was to see if tofacitinib is safe…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New Sjögren's drug shows promise in Mid-Stage trial
Disease control OngoingThis study tests an experimental drug called HZN-1116 in 209 adults with Sjögren's syndrome, an autoimmune disease that causes dry eyes and mouth. Participants receive either the drug or a placebo to see if it reduces disease activity and improves symptoms like pain. The goal is …
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Amgen • Aim: Disease control
Last updated May 07, 2026 18:39 UTC
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Shingles vaccine shows promise for patients with rheumatic conditions
Prevention OngoingThis study looks at how safe and effective the Shingrix vaccine is for people with autoimmune rheumatic diseases like rheumatoid arthritis and lupus, who are at higher risk for shingles. About 2,000 participants will receive the vaccine or a placebo to check for disease flares an…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE4 • Sponsor: University of Sao Paulo General Hospital • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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Gut check: could your microbiome hold the key to Sjogren's Flare-Ups?
Knowledge-focused OngoingThis study explores whether changes in gut bacteria can affect Sjogren's syndrome, an autoimmune disease causing dry eyes, dry mouth, and fatigue. Researchers will measure certain proteins in the blood that indicate gut leakage, and see if they relate to disease activity. The goa…
Matched conditions: SJOGREN'S SYNDROME
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Saliva and blood tests could unlock Sjögren's mysteries
Knowledge-focused OngoingThis study looks at immune markers in the saliva and blood of 80 people with primary Sjögren's syndrome, a chronic autoimmune disease causing dry eyes and mouth. Researchers will measure antibodies and enzyme activity before and after treatment for gum disease. The goal is to lea…
Matched conditions: SJOGREN'S SYNDROME
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Arthritis study tackles missed appointments with personalized help
Knowledge-focused OngoingThis study looks at whether giving people with inflammatory arthritis extra support—like a list of local resources, help from a community specialist, or a nurse navigator—can reduce missed doctor visits. About 100 adults with conditions like rheumatoid arthritis or lupus who have…
Matched conditions: SJOGREN'S SYNDROME
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC