SJOGREN'S SYNDROME

This study tested a new medicine called SAR441344 in 84 adults with primary Sjögren's syndrome, an autoimmune disease causing dry eyes, dry mouth, and fatigue. Participants received either the drug or a placebo for 12 weeks. The goal was to see if the drug reduces disease activit…

This study tested whether baricitinib, a drug that calms the immune system, can help people with active Sjogren's syndrome. About 87 adults were randomly assigned to take either hydroxychloroquine alone or baricitinib with or without hydroxychloroquine for 24 weeks. The goal was …

This study looked at the safety of two doses of iscalimab in 206 people with Sjögren's syndrome who had already completed a previous study. The main goal was to track any side effects. Researchers also measured how much drug stayed in the blood and checked for signs of effectiven…

This study tested whether an experimental drug called nipocalimab could reduce disease activity and symptoms in adults with primary Sjogren's syndrome, an autoimmune condition that causes severe dryness, fatigue, and pain. Researchers compared nipocalimab against a placebo in 163…

This study tested an artificial intelligence (AI) program designed to help doctors diagnose Sjogren's syndrome. The AI analyzes images of minor salivary gland biopsies to count immune cells, a key sign of the disease. Researchers compared the AI's results to those of expert patho…

This study looked at whether regular aerobic exercise (like walking or cycling) can reduce fatigue in women with primary Sjögren's syndrome, a condition that causes dryness and tiredness. 45 women participated in a 16-week program. Researchers measured changes in fatigue, mood, q…

This study looked at whether removing wheat from the diet can reduce symptoms like pain, fatigue, and dryness in people with Sjogren's syndrome. Thirty adults with Sjogren's followed a wheat-free diet for a period, and researchers measured changes in their symptoms and inflammati…

This small study tested whether levocarnitine, a natural substance, can help relieve dry eye in people with Sjogren's syndrome. Fifteen adults each received both the supplement and a placebo in a crossover design. Researchers measured changes in eye inflammation and dry eye sympt…

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers used a questionnaire to track 10 different digestive symptoms in 151 adults. The goal was to better understand these hidden symptoms and how they relate to the disease.