SJOGREN'S SYNDROME
Clinical trials for SJOGREN'S SYNDROME explained in plain language.
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New drug tested to tame autoimmune attack in Sjögren's
Disease control CompletedThis study tested an experimental drug called SAR441344 to see if it could safely reduce disease activity and symptoms like fatigue in adults with primary Sjögren's syndrome. For 12 weeks, 84 participants received either the drug or a placebo (inactive substance) in a double-blin…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Extended trial tests promising Sjögren's syndrome injection
Disease control CompletedThis study continued testing an experimental drug called iscalimab in people with Sjögren's syndrome who had already taken it in a previous trial and seemed to benefit. For about a year, 206 participants received regular injections of one of two doses to closely monitor safety an…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New drug trial targets root cause of debilitating autoimmune disease
Disease control CompletedThis study tested whether an experimental drug called nipocalimab could reduce disease activity and symptoms in adults with primary Sjogren's syndrome, an autoimmune condition that causes severe dryness, fatigue, and pain. Researchers compared nipocalimab against a placebo in 163…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New pill tested to tame autoimmune dryness disease
Disease control CompletedThis study tested whether a pill called baricitinib could help control the disease activity and ease symptoms in people with active primary Sjogren's syndrome, an autoimmune disorder that causes severe dryness and fatigue. About 87 adults with moderate disease activity were rando…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Study tests if simple walking eases debilitating fatigue in autoimmune disease
Symptom relief CompletedThis study tested whether a regular walking program could help reduce the severe fatigue often experienced by women with primary Sjögren's syndrome. Forty-five women were randomly assigned to either a 16-week supervised walking program or a control group that did not exercise ini…
Matched conditions: SJOGREN'S SYNDROME
Phase: NA • Sponsor: Samira Tatiyama Miyamoto, PhD • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Could a common supplement be the key to relieving painful dry eye?
Symptom relief CompletedThis small, completed study tested whether an oral supplement called levocarnitine could help treat severe dry eye in adults with Sjogren's syndrome, an autoimmune disease. All 15 participants tried both the supplement and a placebo pill in a crossover design. The main goal was t…
Matched conditions: SJOGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Mar 20, 2026 14:47 UTC