SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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CRISPR gene editing offers hope for blood disorder patients
Disease control Recruiting nowThis study tests a single dose of a CRISPR-modified stem cell therapy (CTX001) in 26 people with transfusion-dependent β-thalassemia or severe sickle cell disease. The treatment uses the patient's own blood stem cells, edited to produce fetal hemoglobin, aiming to reduce or elimi…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE3 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Disease control
Last updated May 17, 2026 04:14 UTC
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Weekly pill trial aims to ease agonizing bone pain for sickle cell patients
Disease control Recruiting nowThis study is testing if a weekly pill called alendronate is safe and can help adults with sickle cell disease who have a painful bone condition called osteonecrosis. Researchers will give the pill to about 30 participants for 6 months to see if it reduces pain and improves bone …
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Apr 13, 2026 20:21 UTC
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Blood donors needed to speed up sickle cell drug discovery
Knowledge-focused Recruiting nowThis study collects blood samples from 250 adults with sickle cell disease, sickle cell trait, and healthy volunteers. Researchers will use the samples to test thousands of compounds, including existing FDA-approved drugs, to find new treatments for sickle cell disease. Participa…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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New study tracks Long-Term effects of sickle cell drug on puberty and fertility
Knowledge-focused Recruiting nowThis study follows 250 people with sickle cell anemia over many years to see how the medicine hydroxyurea affects their growth, puberty, and ability to have children. Researchers will also compare pregnancy outcomes between those who take the drug and those who don't. The goal is…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC
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Sickle cell Kids' measles protection under the microscope
Knowledge-focused Recruiting nowThis study looks at whether infants and young children with sickle cell disease (SCD) get enough protection from the standard measles vaccine. Researchers will measure antibody levels in 130 children with SCD after they receive their routine measles shots. The goal is to understa…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC