SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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Double transplant from same donor could reduce lifelong Anti-Rejection drugs
Disease control CompletedThis study tested a combined bone marrow and kidney transplant from a partially matched related donor for 10 people with both a blood disorder and chronic kidney disease. The goal was to treat both conditions and possibly reduce the need for lifelong anti-rejection drugs after th…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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New pill aims to boost fetal hemoglobin in sickle cell patients
Disease control CompletedThis early-stage study tested a new drug, Pociredir (FTX-6058), in 45 adults with sickle cell disease. The main goal was to check safety and how the body processes the drug. Researchers also looked at whether it could increase fetal hemoglobin, which may help reduce painful crise…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE1 • Sponsor: Fulcrum Therapeutics • Aim: Disease control
Last updated May 01, 2026 16:01 UTC
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New hope for sickle cell pain? drug shows promise in kids and teens
Symptom relief CompletedThis study tested a drug called canakinumab in 49 children and young adults (ages 8-20) with sickle cell anemia to see if it could reduce their daily pain. Participants rated their pain on a scale of 0 to 10, and researchers compared changes over 8 to 12 weeks. The goal was to fi…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 17, 2026 02:03 UTC
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Sickle cell study reveals blood vessel clues
Knowledge-focused CompletedThis completed study looked at how problems with small and large blood vessels relate to the severity of sickle cell disease in adults. Researchers measured blood flow and artery stiffness in 49 participants. The goal was to better understand the disease, not to test a new treatm…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated May 17, 2026 02:04 UTC
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Can a simple quiz spot brain fog in sickle cell patients?
Knowledge-focused CompletedThis study looked at whether a short test called the Montreal Cognitive Assessment (MoCA) can help find thinking and memory problems in adults with sickle cell disease. Researchers compared the MoCA results with a full set of detailed brain tests in 65 participants. The goal was …
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 17, 2026 02:00 UTC
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Sickle cell patients face hidden heart risk: landmark study reveals prevalence
Knowledge-focused CompletedThis study looked at nearly 1,000 adults with sickle cell anemia to find out how many also develop pulmonary hypertension, a condition where blood pressure in the lungs is too high. Participants had heart ultrasounds and blood tests, and were followed by phone for up to 3 years. …
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC