SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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One donor, two transplants: experimental procedure aims to cure blood cancer and fix kidneys
Disease control CompletedThis pilot study tested a combined transplant from a partially matched family donor. It aimed to treat patients who had both a serious blood disorder (like leukemia) and advanced kidney disease at the same time. The goal was to cure the blood disorder and restore kidney function …
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New pill tested to fight sickle cell disease
Disease control CompletedThis early-stage study tested the safety and effects of an experimental oral medication called FTX-6058 in adults with sickle cell disease. Forty-five participants took the daily pill for 12 weeks while researchers monitored for side effects and measured how the drug affected the…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE1 • Sponsor: Fulcrum Therapeutics • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Quick brain check for sickle cell patients
Diagnosis CompletedThis study aimed to see if a short, 10-minute screening test could reliably detect thinking and memory problems in adults with sickle cell disease. Researchers tested 65 adults with sickle cell disease, comparing the results of the quick screening test to a much longer, detailed …
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Mar 23, 2026 15:19 UTC
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New shot tested to ease agony of sickle cell disease in kids
Symptom relief CompletedThis study tested whether monthly injections of a drug called canakinumab could reduce the daily pain and inflammation experienced by children and young adults with sickle cell anemia. For 24 weeks, 49 participants aged 8-20 received either the drug or a placebo (dummy shot) to s…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Landmark study tracks deadly complication in sickle cell patients
Knowledge-focused CompletedThis study aimed to find out how common and serious high blood pressure in the lungs (pulmonary hypertension) is for adults with sickle cell disease. Researchers enrolled 986 adults to check their heart health with an ultrasound and then followed up with phone calls for over thre…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists probe hidden link between blood vessels and sickle cell pain crises
Knowledge-focused CompletedThis study aimed to understand how problems with small and large blood vessels affect the severity of sickle cell disease in adults. Researchers measured blood flow, artery stiffness, and physical fitness in 49 participants with sickle cell anemia to see how these factors relate …
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC