New sickle cell drug shows promise in early safety trial
NCT ID NCT05169580
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested a new drug, Pociredir (FTX-6058), in 45 adults with sickle cell disease to see if it is safe and how the body processes it. The main goal was to check for side effects and measure drug levels in the blood. Researchers also looked at changes in fetal hemoglobin, which may help control the disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Barau Dikko Teaching Hospital
Kaduna, 800125, Nigeria
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Charlotte Maxeke Johannesburg Academic Hospital
Johannesburg, 2193, South Africa
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Eastern Carolina University
Greenville, North Carolina, 27834, United States
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Inova Schar Cancer Institute
Fairfax, Virginia, 22031, United States
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Jacobi Medical Center
The Bronx, New York, 10461, United States
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Lynn Health Science Institute
Oklahoma City, Oklahoma, 73112, United States
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National Hospital, Abuja
Abuja, 900247, Nigeria
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Our Lady of the Lake Hospital
Baton Rouge, Louisiana, 70808, United States
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Queens Hospital Cancer Center
Jamaica, New York, 11432, United States
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Sonar Research Center
Atlanta, Georgia, 30315, United States
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University of Arkansas for Medical Sciences (UAMS)
Little Rock, Arkansas, 72205, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of Ibadan
Ibadan, 200212, Nigeria
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University of Illinois Chicago
Chicago, Illinois, 60612, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Texas Houston
Houston, Texas, 77030, United States
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Virginia Commonwealth University
Richmond, Virginia, 23298, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Co-Designed support help parents embrace sickle cell care?
- Can community hospitals in zambia master severe disease care?
- A Pocket-Sized coach for sickle cell: can an app turn Pill-Taking into a habit?
- Can a phone app keep teens on track with sickle cell treatment?
- A common amino acid may calm sickle cell pain crises — a trial puts it to the test
- A drug that protects the liver may make stem cell transplants safer for children with sickle cell disease