New hope for sickle cell pain: canakinumab shows promise in kids
NCT ID NCT02961218
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called canakinumab (ACZ885) in 49 children and young adults aged 8-20 with sickle cell anemia. The goal was to see if it could reduce daily pain compared to a placebo. Participants rated their pain daily using a 0-10 scale, and researchers measured changes over 12 weeks. The trial was completed and focused on safety and pain relief.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Novartis Investigative Site
Atlanta, Georgia, 30329, United States
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Novartis Investigative Site
Augusta, Georgia, 30912, United States
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Novartis Investigative Site
Greenville, North Carolina, 27834, United States
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Novartis Investigative Site
Toronto, Ontario, M5G 1X8, Canada
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Novartis Investigative Site
Hamburg, 20246, Germany
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Novartis Investigative Site
Afula, 1834111, Israel
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Novartis Investigative Site
Johannesburg, Guateng, 2193, South Africa
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Novartis Investigative Site
Adana, 01330, Turkey (Türkiye)
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Novartis Investigative Site
Ankara, 06100, Turkey (Türkiye)
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Novartis Investigative Site
Mersin, 33343, Turkey (Türkiye)
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Novartis Investigative Site
Wolverhampton, Staffordshire, WS11 5XY, United Kingdom
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Novartis Investigative Site
London, E1 1BB, United Kingdom
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Novartis Investigative Site
London, NW1 2BU, United Kingdom
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Novartis Investigative Site
London, SE1 7EH, United Kingdom
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Novartis Investigative Site
London, SE5 9RS, United Kingdom