New hope for sickle cell pain? drug shows promise in kids and teens

NCT ID NCT02961218

First seen Jan 14, 2026 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tested a drug called canakinumab in 49 children and young adults (ages 8-20) with sickle cell anemia to see if it could reduce their daily pain. Participants rated their pain on a scale of 0 to 10, and researchers compared changes over 8 to 12 weeks. The goal was to find a safer, more tolerable way to manage sickle cell pain.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Atlanta, Georgia, 30329, United States

  • Novartis Investigative Site

    Augusta, Georgia, 30912, United States

  • Novartis Investigative Site

    Greenville, North Carolina, 27834, United States

  • Novartis Investigative Site

    Toronto, Ontario, M5G 1X8, Canada

  • Novartis Investigative Site

    Hamburg, 20246, Germany

  • Novartis Investigative Site

    Afula, 1834111, Israel

  • Novartis Investigative Site

    Johannesburg, Guateng, 2193, South Africa

  • Novartis Investigative Site

    Adana, 01330, Turkey (Türkiye)

  • Novartis Investigative Site

    Ankara, 06100, Turkey (Türkiye)

  • Novartis Investigative Site

    Mersin, 33343, Turkey (Türkiye)

  • Novartis Investigative Site

    Wolverhampton, Staffordshire, WS11 5XY, United Kingdom

  • Novartis Investigative Site

    London, E1 1BB, United Kingdom

  • Novartis Investigative Site

    London, NW1 2BU, United Kingdom

  • Novartis Investigative Site

    London, SE1 7EH, United Kingdom

  • Novartis Investigative Site

    London, SE5 9RS, United Kingdom

Conditions

Explore the condition pages connected to this study.