RETROPERITONEAL SARCOMA

This study is testing a new way of giving radiation before surgery for a rare type of cancer called retroperitoneal sarcoma. The goal is to see if this approach is safe and reduces complications during and after surgery. About 50 adults with this cancer will receive focused radia…

This early-phase trial tests the safety and best dose of the drug abemaciclib when given with radiation therapy before surgery for a rare, high-risk type of abdominal cancer called retroperitoneal sarcoma. The study enrolls 18 adults whose tumors have certain genetic markers. The…

This study tests a new way to give radiation before surgery for retroperitoneal sarcoma, a rare tumor deep in the abdomen. About 80 adults will receive either proton or photon radiation, with a higher dose to high-risk areas of the tumor. The goal is to find the safest highest do…

This study tests whether giving chemotherapy before surgery helps people with high-risk retroperitoneal sarcoma (a rare cancer in the abdomen) live longer without the cancer coming back. About 250 adults with specific sarcoma types will be randomly assigned to receive chemo then …

This study tests a new type of proton radiation called P-SFRT, given alongside standard radiation, for people with a rare cancer called retroperitoneal sarcoma. The goal is to find the safest dose and see if it helps shrink tumors before surgery. About 28 adults with newly diagno…

This study tests a treatment called electrochemotherapy for people with tumors in organs like the liver or pancreas that cannot be removed with surgery. The treatment uses short electric pulses to help chemotherapy drugs enter cancer cells more effectively. The goal is to see if …

This early-phase trial tests a shorter, more intense radiation schedule for people with retroperitoneal sarcoma, a rare cancer in the abdomen. The main goal is to see if this approach is safe by tracking side effects like nausea and diarrhea within 30 days. Only 6 participants wi…

This study looks at tissue and imaging data from 800 people with high-risk soft tissue sarcoma to find ways to personalize chemotherapy. Participants either have surgery alone or chemo before surgery. The goal is to build a tumor atlas and a tool to predict who benefits from chem…

This study looks at different surgical methods for removing colorectal parts during treatment for retroperitoneal sarcoma, a rare cancer in the abdomen. Researchers will track complications and use surveys to measure patients' quality of life after surgery. The goal is to help su…