RENAL INSUFFICIENCY CHRONIC

This study tests whether time-restricted eating (eating only during a set window each day) can reduce protein in the urine and slow kidney function decline in people with moderate chronic kidney disease. About 50 adults with stage 2-3 CKD and elevated albuminuria will follow the …

This study tests whether a 12-week supervised exercise program done during dialysis can improve muscle mass, strength, sleep, and quality of life in adults over 40 with chronic kidney disease. Participants are randomly assigned to either an exercise group or standard care. The go…

This study tests whether an artificial intelligence (AI) program can help people on dialysis feel less anxious and better cope with stress. Sixty adults on maintenance hemodialysis will use personalized relaxation techniques guided by AI during their sessions. Researchers will me…

This study tests a single dose of hydroxynidone, an experimental drug for liver scarring, in 56 adults with mild to severe kidney problems and healthy volunteers. Researchers want to see how the drug moves through the body and if it is safe when kidneys are not working well. The …

This study looks at how the drug eloralintide moves through the body in people with severe kidney disease or kidney failure compared to healthy people. About 28 adults will get a single shot under the skin and be monitored for about 14 weeks. The goal is to understand dosing and …

This study looks at whether a home-based exercise program is safe and practical for adults aged 60 and older who are waiting for a kidney transplant. Participants will wear an activity tracker and may be assigned to online exercise classes or usual care. The goal is to see if the…

This study is for people who have had a liver transplant and now have kidney issues. Researchers will use kidney biopsies to learn why kidney problems happen and how they get worse over time. The goal is to better understand the disease, not to test a new treatment.

This study looks at kidney tissue from adults with diabetic kidney disease who are already having a kidney biopsy or surgery. Researchers want to understand how SGLT2 inhibitors, a common diabetes medicine, change the kidney's molecular makeup. Participants donate a tissue slide,…

This study looks at how calcium and phosphorus from food affect people with advanced chronic kidney disease (stages 4 and 5). Researchers will compare two ways of tracking what patients eat: taking photos of meals versus writing down everything. The goal is to better understand t…

This study aims to better understand how donated kidneys perform after transplant and how a donor's remaining kidney adapts. Researchers will use special MRI scans to measure blood flow, oxygen levels, and tissue health in 60 participants (both donors and recipients). The goal is…