RENAL INSUFFICIENCY, CHRONIC

This pilot study tests whether time-restricted eating (eating all meals within an 8-hour window each day) can reduce protein in the urine and slow kidney function decline in people with moderate chronic kidney disease. Fifty adults with stage 2-3 CKD and elevated albuminuria will…

This study tests whether an artificial intelligence (AI) program can help people on dialysis feel less anxious and cope better with stress. About 60 adults will use personalized relaxation techniques guided by AI during their dialysis sessions. Researchers will measure changes in…

This study tests whether a 12-week home-based exercise program is safe and practical for adults aged 60 and older who are waiting for a kidney transplant. Participants will either receive usual care plus a physical activity tracker, or usual care plus the tracker and online exerc…

This study tests whether a 12-week supervised exercise program done during dialysis can improve muscle mass, strength, sleep, and quality of life in adults over 40 with chronic kidney disease. Participants are randomly assigned to either exercise during the first 90 minutes of di…

This study uses special MRI scans to look at how well a donated kidney works in the recipient and how the donor's remaining kidney adapts over one year. It includes 80 adults (donors and recipients) and aims to help doctors choose the best kidneys for transplant. The goal is to b…

This study looks at why people with chronic kidney disease (CKD) have trouble exercising and often experience high blood pressure during physical activity. Researchers will test whether regular cycling exercise, a drug called Kuvan, or supplements like histidine and beta-alanine …

This study tests a single dose of hydroxynidone capsules in 56 people with different levels of kidney function and healthy volunteers. The goal is to see how the drug moves through the body and if it is safe in people with kidney problems. Participants will have blood and urine t…

This study looks at how the drug eloralintide enters the bloodstream and leaves the body in people with severe kidney disease or kidney failure, compared to healthy volunteers. About 28 participants will receive a single shot under the skin. The study lasts about 14 weeks and doe…

This observational study examines kidney tissue from adults with diabetic kidney disease who are already having a kidney biopsy or surgery as part of their regular care. Researchers want to see if people taking SGLT2 inhibitors (a type of diabetes medicine) show different biologi…

This study aims to understand the link between calcium and phosphorus from food and the stage of kidney disease in patients with advanced chronic kidney disease (stage 4-5). Researchers will compare two methods of tracking diet: taking photos of meals and weighing food. The goal …

This study is for adults who have had a liver transplant and now have kidney issues. Researchers want to learn how often kidney function gets worse and what factors might cause that decline. They will look at results from kidney biopsies already done in the past 3 months. The goa…