RECURRENT HIGH GRADE GLIOMA
Clinical trials for RECURRENT HIGH GRADE GLIOMA explained in plain language.
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Brain tumor chemo delivered by pump shows promise in tiny safety trial
Disease control CompletedThis early-phase study tested whether pumping the chemotherapy drug topotecan directly into the brain is safe for people with recurrent high-grade gliomas (aggressive brain tumors). Only 5 patients took part, and the main goal was to find a safe dose. The drug was delivered conti…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New cocktail aims to shrink deadly brain tumors
Disease control CompletedThis phase 2 trial tested a combination of two drugs (retifanlimab and epacadostat) plus radiation and bevacizumab in 51 patients with recurrent glioblastoma, an aggressive brain cancer. The goal was to boost the immune system's attack on the tumor and improve survival. The study…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New scan could reveal brain tumor aggression without surgery
Diagnosis CompletedThis study tested a special PET scan tracer called FLT in 50 adults with brain tumors (gliomas or metastases). The goal was to see if FLT-PET can measure how fast tumor cells are growing, which could help doctors diagnose and predict tumor behavior better than current scans like …
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: NA • Sponsor: University Hospital, Caen • Aim: Diagnosis
Last updated Jun 27, 2026 12:03 UTC
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New dye could sharpen PET scans for recurrent brain cancer
Diagnosis CompletedThis study tested whether a special dye called fluoroethyltyrosine (FET) can improve PET scans for detecting brain tumors that have come back. 143 people with suspected recurrent brain tumors received an injection of FET before their PET scan. The goal was to see if FET-PET could…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE2 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC