RECURRENT HIGH GRADE GLIOMA
Clinical trials for RECURRENT HIGH GRADE GLIOMA explained in plain language.
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Virus therapy takes on deadly brain cancer
Disease control ENROLLING_BY_INVITATIONThis study tests a modified virus (BioTTT001) injected directly into brain tumors in 30 adults with recurrent high-grade glioma. The goal is to see if it is safe, how it spreads in the body, and whether it can help control the cancer. Participants will receive multiple injections…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: Beijing Bio-Targeting Therapeutics Technology Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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RNA vaccine fights childhood cancers in new trial
Disease control OngoingThis study tests a new RNA-lipid particle vaccine for children and young adults (ages 3-25) with recurrent high-grade glioma or osteosarcoma that has spread to the lungs. The vaccine is made from the patient's own tumor material and aims to train the immune system to attack the c…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Stem cells and immunotherapy join forces against childhood brain tumors
Disease control OngoingThis early-stage trial tests a new approach for children whose high-grade glioma has come back after standard treatments. It combines specially grown stem cells with an immunotherapy drug called nivolumab. The main goals are to see if the treatment is safe and possible to deliver…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can a pill get into brain tumors? tiny study aims to find out
Knowledge-focused OngoingThis early study tests whether the drug abemaciclib can be measured inside brain tumors after being taken by mouth. One person aged 18–39 with a recurrent high-grade glioma or diffuse midline glioma will take the drug for 4.5 days before surgery. During surgery, a small tube is p…
Matched conditions: RECURRENT HIGH GRADE GLIOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC