RECTAL CANCER
Clinical trials for RECTAL CANCER explained in plain language.
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Rearranging the treatment timeline: could a new sequence of chemo and radiation spare rectal cancer patients from major surgery?
Disease control TerminatedThis trial is testing whether giving chemotherapy before the standard combination of chemo and radiation for rectal cancer could allow some patients to have a minor surgical procedure instead of a major one. The study enrolls adults with stage T2-T3 rectal cancer. The goal is to …
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Rectal cancer: could a 'Watch and Wait' strategy spare patients from major surgery?
Disease control TerminatedThis trial is testing whether a 'watchful waiting' approach after chemotherapy and radiation can safely avoid radical surgery in people with a certain type of rectal cancer. Participants receive chemotherapy (FOLFOX) followed by chemo-radiation, and those whose tumors completely …
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Experimental cell therapy targets tough cancers, but trial ends early
Disease control TerminatedThis early-phase trial tested a new approach: taking a patient's own white blood cells, genetically modifying them in the lab to recognize a specific cancer mutation (KRAS G12D), and infusing them back to attack tumors. The study enrolled only 5 adults with advanced gastrointesti…
Matched conditions: RECTAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New stoma technique aims to ease bowel troubles after rectal cancer surgery
Disease control TerminatedThis study tested a new type of temporary colostomy (a surgical opening in the belly) for people having rectal cancer surgery. The goal was to see if it could reduce bowel problems and kidney injury compared to the usual stoma. Only 16 patients were enrolled before the study was …
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: Umeå University • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New gel aims to stop deadly leaks after bowel surgery
Disease control TerminatedThis study tested a new gel called Dehisgel in 20 adults who had colorectal surgery for rectal cancer. The goal was to see if the gel could safely prevent leaks where the bowel was reconnected. The study was stopped early, so results are limited.
Matched conditions: RECTAL CANCER
Sponsor: Contipro Pharma a.s. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Can an ultrasound predict who can skip surgery for rectal cancer?
Diagnosis TerminatedThis study tested whether a special ultrasound technique (D-CEUS) can predict how well rectal cancer responds to chemotherapy and radiation. The goal is to identify good responders who might avoid major surgery and instead have a less invasive procedure. Only 2 people took part, …
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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Pre-Surgery pelvic floor training may prevent devastating bowel issues in rectal cancer patients
Prevention TerminatedThis study looked at whether doing pelvic floor exercises with biofeedback before rectal cancer surgery could prevent a condition called Low Anterior Resection Syndrome (LARS), which causes bowel control problems like leakage and urgency. The study planned to include 120 adults a…
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: Nantes University Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:10 UTC
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Short radiation course for rectal cancer aims to ease side effects
Symptom relief TerminatedThis study tested a short course of targeted radiation (IMRT) given over one week before surgery for rectal cancer. The goal was to see if this approach could reduce side effects like bowel problems and improve quality of life compared to standard longer treatments. Only 2 people…
Matched conditions: RECTAL CANCER
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC