PULPITIS
Clinical trials for PULPITIS explained in plain language.
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New tooth-saving technique matches root canal success in study
Disease control CompletedThis study compared two ways to treat badly inflamed tooth pulp: a newer method called vital pulp therapy (VPT) and the standard root canal treatment (RCT). 43 adults with painful, deep cavities took part and were followed for one year. Both treatments aimed to save the tooth and…
Matched conditions: PULPITIS
Phase: NA • Sponsor: Universidad Central de Venezuela • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Pill vs. drill: new study tests steroid as alternative to root canal for tooth pain
Symptom relief CompletedThis study compared taking an oral steroid (prednisolone) for three days to getting a partial root canal for emergency pain relief from severe tooth nerve inflammation (pulpitis). The goal was to see if the pill could work as well as the dental procedure. Only 5 people were enrol…
Matched conditions: PULPITIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 17, 2026 01:26 UTC
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Light therapy may ease root canal pain, study finds
Symptom relief CompletedThis study looked at whether using a special light treatment (photodynamic therapy, or PDT) during a root canal can lower pain afterward. 95 adults with infected back teeth were treated, and their pain was tracked for 3 days. The goal was to see if adding PDT to standard cleaning…
Matched conditions: PULPITIS
Sponsor: Atlas University • Aim: Symptom relief
Last updated Jun 16, 2026 12:48 UTC
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Can AI help save more teeth? new study tests pulpotomy vs root canal
Symptom relief CompletedThis study looked at whether a less invasive dental procedure called full pulpotomy can work as well as a root canal for treating severe tooth inflammation. Researchers treated 58 adults with painful, inflamed molars, some with and some without a related infection at the tooth ro…
Matched conditions: PULPITIS
Phase: NA • Sponsor: Misr International University • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Cold therapy may ease pain after root canal, study finds
Symptom relief CompletedThis study tested whether applying cold (cryotherapy) during pulpotomy or root canal treatment reduces pain and improves quality of life. 144 adults with deep cavities in their molars were randomly assigned to receive either standard treatment or treatment with added cryotherapy.…
Matched conditions: PULPITIS
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 09, 2026 12:08 UTC
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Tooth inflammation study seeks biomarkers to improve diagnosis
Knowledge-focused CompletedThis study measured three inflammation-related proteins (IL-8, FGF-1, and VEGF) in the teeth of 51 people with healthy pulp, mild tooth inflammation, or severe tooth inflammation. Samples were taken from the tooth's inner tissue, gum fluid, and dentin fluid during routine root ca…
Matched conditions: PULPITIS
Sponsor: Kırıkkale University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Tooth pain tied to stress chemicals, study finds
Knowledge-focused CompletedThis study looked at 72 adults with and without tooth pain to measure certain nerve chemicals (substance P and CGRP) in their saliva and tooth pulp. Researchers wanted to see how these chemicals relate to pain severity, tooth inflammation, and psychological factors like anxiety a…
Matched conditions: PULPITIS
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC