PRIMARY HYPERTENSION

This Phase 2 trial tests a new drug called HDY015, which combines two medicines (QCZ484 and inclisiran) into a single injection. The goal is to see if it can safely lower both blood pressure and cholesterol in people who have both conditions. About 120 adults aged 18-75 with hype…

This study tests whether powerful weight loss drugs (like semaglutide or tirzepatide) can lower blood pressure enough for young adults (ages 18-40) with obesity and early-stage hypertension to stop taking daily blood pressure pills. Sixty participants will either receive the weig…

This study is testing whether inhaling lavender oil three times a week for a month can reduce anxiety, improve sleep quality, and lower blood pressure in people with primary hypertension. Fifty participants will be randomly assigned to either receive lavender oil inhalation plus …

This study looks at how bacteria in the mouth might help control blood pressure in children aged 10-18 with high blood pressure. Researchers will collect saliva and do simple mouth exams to compare these children with healthy peers. No drugs or treatments are given—the goal is to…

This study looks at whether three common blood pressure medications (beta-blockers, ACE inhibitors, and calcium channel blockers) affect balance and fall risk in adults newly diagnosed with high blood pressure. About 186 participants will be randomly assigned to one of the three …

Primary aldosteronism is a common but often missed cause of high blood pressure. This study will analyze blood, urine, and adrenal tissue from 400 people to find biological markers that could lead to earlier diagnosis. Researchers hope to use advanced lab techniques and machine l…

This study is looking at children ages 7 to 18 who have been newly diagnosed with high blood pressure. Researchers want to understand how certain hormones in the body, like angiotensin-(1-7), may contribute to damage in the heart, kidneys, and blood vessels. Over two years, they …