PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC patients: drug aims to normalize liver enzyme levels
Disease control OngoingThis study tests a daily pill called elafibranor in adults with primary biliary cholangitis (PBC) whose current treatment isn't working well enough or causes side effects. The main goal is to see if elafibranor can bring a key liver enzyme (ALP) back to normal levels. About 69 pa…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated May 17, 2026 03:30 UTC
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New hope for bile duct disease: experimental drug K-808 tested in patients failed by standard care
Disease control OngoingThis study tests whether a new drug called K-808 (Pemafibrate) can improve liver health in people with primary biliary cholangitis (PBC), a chronic liver disease. The trial includes 46 adults whose disease did not respond well to standard medications. Participants receive either …
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Kowa Research Institute, Inc. • Aim: Disease control
Last updated May 17, 2026 03:26 UTC
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New hope for PBC patients: extended trial of saroglitazar shows promise
Disease control OngoingThis study looks at the long-term safety and effectiveness of the drug saroglitazar magnesium in people with primary biliary cholangitis (PBC), a chronic liver disease. About 102 adults who completed a previous study are taking the drug for up to 2 more years. Researchers are tra…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for PBC patients: daily pill aims to protect the liver
Disease control OngoingThis study tests a daily pill called elafibranor in 18 Japanese adults with primary biliary cholangitis (PBC), a chronic liver disease. The goal is to see if the drug can lower two key markers of liver damage (ALP and bilirubin) over a year, with long-term follow-up. Participants…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New drug combo shows promise for rare liver disease
Disease control OngoingThis study tests whether adding fenofibrate to standard treatment (ursodeoxycholic acid) can improve liver health and reduce itching in people with primary biliary cholangitis (PBC), a chronic liver disease. About 184 adults aged 18-75 with PBC will take the combination and be mo…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2, PHASE3 • Sponsor: Han Ying • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New reflex test could spot silent liver disease in thousands of women
Diagnosis OngoingThis study looks at whether a two-step blood test can help doctors find primary biliary cholangitis (PBC) earlier in women over 40 who are at risk. PBC is a chronic liver disease that often has no early symptoms, leading to delayed diagnosis. The test automatically checks for spe…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated May 15, 2026 11:53 UTC