PRIMARY BILIARY CHOLANGITIS
Clinical trials for PRIMARY BILIARY CHOLANGITIS explained in plain language.
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New hope for PBC patients: experimental drug K-808 enters Mid-Stage trial
Disease control OngoingThis study tests two doses of K-808 (Pemafibrate) in 46 adults with primary biliary cholangitis (PBC) who haven't responded well to standard treatments. The main goal is to see if the drug lowers alkaline phosphatase (ALP) levels, a key marker of liver damage, after 12 weeks. Par…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2 • Sponsor: Kowa Research Institute, Inc. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New hope for liver disease: drug shows promise in reducing damage
Disease control OngoingThis study tests a daily pill called elafibranor in about 18 Japanese adults with primary biliary cholangitis (PBC), a rare liver disease that can lead to scarring and liver failure. Participants had not responded well to standard treatment. The main goal is to see if the drug im…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New drug aims to normalize liver enzyme in bile duct disease
Disease control OngoingThis study tests whether elafibranor, a daily pill, can normalize alkaline phosphatase (ALP) levels in adults with primary biliary cholangitis (PBC) who did not respond well to or cannot take standard treatment. About 69 participants will receive either elafibranor or a placebo f…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Ipsen • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Hope for liver disease: new drug trial targets PBC symptoms
Disease control OngoingThis study tests a drug called saroglitazar magnesium in people with primary biliary cholangitis (PBC), a chronic liver disease. The goal is to see if the drug is safe and helps control the disease. About 102 adults who completed a previous PBC study will take the drug and be mon…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE3 • Sponsor: Zydus Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Could a cholesterol drug help fight a rare liver disease?
Disease control OngoingThis study tests whether adding fenofibrate (a drug used for high cholesterol) to standard treatment with ursodeoxycholic acid can improve liver health in people with primary biliary cholangitis (PBC), a rare autoimmune liver disease. About 184 adults with PBC will receive either…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: PHASE2, PHASE3 • Sponsor: Han Ying • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Simple blood test could spot hidden liver disease in women
Diagnosis OngoingThis study is testing a reflex blood test to find primary biliary cholangitis (PBC) earlier in women aged 40 and older. When routine blood work shows certain liver enzyme elevations, the lab automatically checks for antibodies linked to PBC. The goal is to see if this automatic f…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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Can a smartwatch help manage a rare liver disease? stanford study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study at Stanford University is testing whether wearable devices like smartwatches can help measure fatigue, sleep, and daily activity in people with primary biliary cholangitis (PBC), a chronic liver disease. Researchers will compare data from the wearables with patient que…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New study tracks blood sugar in liver disease patients on common drug
Knowledge-focused OngoingThis study looks at how a type of medication called PPAR agonists affects blood sugar levels in 30 adults with primary biliary cholangitis (PBC), a chronic liver disease. Researchers will measure changes in blood sugar and other metabolic markers over three months. The goal is to…
Matched conditions: PRIMARY BILIARY CHOLANGITIS
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC